题目:Genome Diversity of Maize and Plant Breeding
报告人:Dr. Antoni Rafalski,Senior Research Fellow at Pioneer Hi-Bred, DuPont Company
报告时间:3月29日（星期二）上午10：00
报告地点: B-210
联 系 人: 曹晓风
联系电话: 010-64869203
欢迎大家踊跃参加！
Abstract:
Technological discoveries and improvements frequently drive the progress in science. Such was the case with the invention of the microscope. It is also demonstrably true with the exponential increases in the capacity to sequence nucleic acids. Only a few years ago genotyping population was a major challenge, as was the discovery of sufficient number of genetic markers. Now, second generation sequencing technology provides easy access to a large number of SNP markers which can be converted to highly multiplexed assays. Already some large organizations and academic labs are using a combination of high throughput sequencing technologies to sequence modest-size germplasm collections. Progress in precision phenotyping has been much slower and remains a major challenge; even though automated phenotyping facilities are becoming available not only to industry but also to academic laboratories. In this talk I will review properties of the different components of genetic diversity that are being discovered by a variety of methods including reduced representation sequencing, comparative genomic hybridization, whole genome sequencing and epigenetic analysis. I will show how we use this information to develop tools to improve the understanding of the relationship between the genotype and phenotype in the applied breeding context and to develop genetic diagnostic tools for maize breeders.
Brief biography: J. Antoni Rafalski, Dr.
Antoni Rafalski is a Senior Research Fellow at Pioneer Hi-Bred, a DuPont Company, and heads a research group in Wilmington, Delaware (USA) He was born and educated in Poland, where he completed his doctorate. He spent several years as a Visiting Scientist at Yale University, with Prof. Dieter S？ll, before joining DuPont Co. At DuPont Dr. Rafalski was a member of the team which obtained the first DNA sequence of the HIV virus, he was a co-discoverer of RAPD markers, and was involved the development of SSR markers for soy and maize, in plant EST sequencing program, development of maize SNP markers and in genetic association mapping. He is an Adjunct Professor at the Department of Plant and Soil Sciences, University of Delaware, and serves on the editorial board of several journals. His scientific interests include analysis of organization of plant genomes, plant genetic diversity at the DNA sequence level, evolutionary history of maize, genetic mapping of traits of agronomic interest and application of molecular techniques in plant breeding.
