姓  名: 戴建武
    职  称: 研究员
    职  务: 再生医学中心主任
    电话/传真: 86-10-64805610
    电子邮件: jwdai@genetics.ac.cn;

    临床研究病人咨询专用邮箱:dailab@genetics.ac.cn

    微信公众号:中科院再生医学(ID:dailab2003);

    脊髓损伤修复前沿(ID:Spinal-cord-repair)
    实验室主页: http://dailab.genetics.ac.cn
    研究方向: 再生医学

    简历介绍:

    戴建武,博士,研究员,博士生导师
        教育经历及任职:
        武汉大学生物系细胞生物学专业 本科
        北京医科大学生物物理学专业 硕士
        美国杜克大学细胞生物学专业 博士
        哈佛大学医学院 博士后研究
        2003-至今:中国科学院遗传与发育生物学研究所 研究员
        国家杰出青年基金获得者         
        国家药品监督管理局医疗器械 审评专家          
        中国细胞生物学学会干细胞分会 副会长
        中国生物材料学会第四届理事会 理事
        中国生物材料学会 神经修复材料分会 副主任委员
        中国遗传学会再生医学转化分会 常务副会长
        Biomedical Materials 杂志 主编[J1] 

    研究领域:

    主要研究方向:
        1)基于生物材料的组织器官再生修复产品研发
        2)组织器官制造研究
        2023-2027  国家重点研发计划项目“脊髓损伤修复生物材料产品研发”项目负责人
        2024-2028  国家自然基金委重点项目“仿生/工程化脊髓组织构建与功能调控”项目负责人[J1]
    部分获奖情况:
        2012年:心肌梗死后心肌组织修复和功能重建的机制研究及临床应用,国家科技部,国家科学技术进步奖二等奖
        2014年:中央电视台年度科技创新人物
        2016年:第六届中国侨界再生医学创新成果奖
        2017年:中国细胞生物学学会干细胞生物学分会干细胞成果转化奖
        2018年:子宫内膜再生研究获江苏省科学技术一等奖
    代表性成果
        Ø  突破了再生医学关键技术。研发了系列具有自主知识产权的再生医学产品。研发的基于胶原蛋白特异结合的BMP2活性骨材料成功获得创新医疗器械注册证,实现了0-1的突破。提出组织内源干细胞的激活与分化是组织再生的重要机理。率先成功组织了包括子宫内膜再生、卵巢再生、脊髓损伤再生,心肌再生等多个产品的临床研究。
        Ø  研发的子宫内膜再生修复产品为子宫内膜损伤的不孕患者提供了一种有效的治疗手段,入选2014年中央电视台年度科技创新人物;卵巢再生修复取得突破,第一个卵巢早衰患者2018年1月12日诞生世界上首位健康宝宝。子宫内膜再生卵巢再生及脊髓损伤再生成果入选国家改革开放40周年创新成果展。
        Ø  成功研发了首个脊髓损伤再生修复产品NeuroRegn 支架。NeuroRegn 支架2014年开始临床研究, 长期的临床随访结果表明NeuroRegn 支架治疗急性及陈旧性脊髓损伤安全有效。研究团队成为国际上最受关注的脊髓损伤再生修复研究团队之一。
    工作人员:
    赵燕南  博士   青年研究员
    陈  冰  博士   副研究员
    肖志峰  博士   副研究员
    吴宪明  博士   副研究员
    张  琪  博士   助理研究员
    施  雅  博士   工程师
    侯祥林  硕士   工程师
    尹艳云  硕士   助理工程师
    张  权  学士   技术员
    季纯南  学士   技术员
    博士后:
        尹曼
    博士研究生:
        权瑞  韩舒雨  赵帅净 孙御婷  李雪瑶  刘晨欢  
    硕士研究生:
        赵玉琪  陆珠儿
    客座研究人员:
        崔熠  郭博  周建[J2]
    毕业离所学生:
    索广力 博士 (中科院苏州纳米所)
    张经余 博士  (赛默飞世尔科技)
    赵艳红 博士  (国家药品监督管理局)
    林  航 博士  (匹兹堡大学)
    赵文学 博士  (中山大学)
    王  霞 博士  (清华大学)
    王  斌 博士  (南京大学鼓楼医院)
    孙文杰 博士  (山东大学)
    张  晶 博士  (首都医科大学)
    高  原 博士  (北京宝洁技术有限公司)
    韩倩倩 博士  (中检院)
    高  健 硕士  (雀巢(中国)有限公司)
    曹佳妮 博士 (北京泽辉辰星生物科技有限公司)
    陈  磊 博士 (河南信阳师范学院)
    苏冠男 博士 (重庆医科大学附属第一医院)
    肖汉山 硕士 (天风证券)
    魏建树 博士 (北京301医院)
    杨  赟 博士 (加州大学圣地亚哥分校)
    施春英 博士 (青岛大学)
    李  星 博士 (中南大学)
    刘素梅 博士 (宣武医院)
    栾梁琪 硕士 (宜坤行健医药科技有限公司)
    韩  津 博士 (专利局专利审查协作北京中心)
    杨亚明 博士 (北京大学)
    韩素芳 博士 (华南农业大学)
    薛伟伟 博士 (复旦大学脑科学转化研究院)
    马德尊 博士 (福建中医药大学)
    张海鹏 博士 (苏州益铂生物)
    杨  颖 博士 (福建医科大学)
    范永恒 博士 (西湖大学)
    刘为远 博士 (北京拓界生物医药科技有限公司)
    孙  政 博士 (中国人民解放军第三军医大学)
    媒体报道:(网页视频链接形式)



    社会任职:

    获奖及荣誉:

    承担科研项目情况:

    代表论著:

    近期发表的文章(2015年至今):
    1. Zhang J, Zhou F, Yin Y, Xu B, Zhang Y, Han J, Wu X, Chen B, Xiao Z, Han J, Du J, Zhao Y*, Xia Wang X*, Dai J.* Spinal segment-specific properties of neural stem cells contribute to the outcomes of spinal cord injury repair. Sci China Life Sci. 2024; Accepted.
    2. Sun Z, Chen Z, Yin M, Wu X, Guo B, Cheng X, Quan R, Sun Y, Zhang Q, Fan Y, Jin C, Yin Y, Hou X, Liu W, Shu M, Xue X, Shi Y, Chen B, Xiao Z, Dai J*, Zhao Y*. Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids. Cell Stem Cell. 2024 Mar 26:S1934-5909(24)00089-4.
    3. Xue X, Wu X, Fan Y, Han S, Zhang H, Sun Y, Yin Y, Yin M, Chen B, Sun Z, Zhao S, Zhang Q, Liu W, Zhang J, Li J, Shi Y, Xiao Z*, Dai J*, Zhao Y*. Heterogeneous fibroblasts contribute to fibrotic scar formation after spinal cord injury in mice and monkeys. Nat Commun. 2024; 15(1):6321.
    4. Sun Y, Xiao Z, Chen B, Zhao Y*, Dai J*. Advances in Material-Assisted Electromagnetic Neural Stimulation. Adv Mater. 2024 Apr 9:e2400346.
    5. Liu Z, Lai J, Kong D, Zhao Y, Zhao J, Dai J*, Zhang M*. Advances in electroactive bioscaffolds for repairing spinal cord injury. Biomed Mater. 2024 Apr 30;19(3). doi: 10.1088/1748-605X/ad4079.
    6. Guo B, Zhao X, Zou Y, Cheng X, Sun Z, Xue X, Yin M, Jin C, Chen Z, Quan R, Liu W, Chen B, Xiao Z, Zhao Y*, Gu R*, Dai J*. Evaluation of benefits and risks of immunosuppressive drugs in biomaterial-based neural progenitor cell transplantation for spinal cord injury repair. Chemical Engineering Journal. 487, 2024,150404.
    7. Zhang Q, Zhang L, Weng W, Qiu X, Zhuang Y, Wang H, Wei F, Dai J,* Shen H,* and Chen Y.* Restoration of motor and bladder functions after spinal cord injury via sustained wogonin release from carbon nanotube incorporated hydrogels. ACS Materials Lett. 2024, 6, 3443-3452
    8. Fan C, Cai H, Zhang L, Wu X, Yan J, Jin L, Hu B, He J, Chen Y*, Zhao Y*, Dai J*. Constructing Linear-Oriented Pre-Vascularized human spinal cord tissues for spinal cord injury repair. Adv Healthc Mater. 2024; 13(18):e2303388.
    9. Wu Z, Zhou Y, Hou X, Liu W, Yin W, Wang L, Cao Y, Jiang Z, Guo Y, Chen Q, Xie W, Wang Z, Shi N, Liu Y, Gao X*, Luo L*, Dai J*, Ren C*, Jiang X*. Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair. Bioact Mater. 2024; 35:242-258.
    10. Zhu H, Li T, Xu P, Ding L, Zhu X, Wang B, Tang X, Li J, Zhu P, Wang H, Dai C, Sun H*, Dai J*, Hu Y*. Effect of autologous bone marrow stem cells-scaffold transplantation on the ongoing pregnancy rate in intrauterine adhesion women: a randomized, controlled trial. Sci China Life Sci. 2024 Jan;67(1):113-121.
    11. Xu B, Liu D, Liu W, Long G, Liu W, Wu Y, He X, Shen Y, Jiang P, Yin M, Fan Y, Shen H, Shi L, Zhang Q, Xue W, Jin C, Chen Z, Chen B, Li J, Hu Y, Li X*, Xiao Z*, Zhao Y*, Dai J*. Engineered human spinal cord-like tissues with dorsal and ventral neuronal progenitors for spinal cord injury repair in rats and monkeys. Bioact Mater. 2023 Mar 29; 27:125-137.
    12. Lu C, Wu X, Wang X, Xiao Z, Ma L, Dai J*, Jian F*. Single-cell transcriptomics reveals ependymal subtypes related to cytoskeleton dynamics as the core driver of syringomyelia pathological development. iScience. 2023 May 11;26(6):106850.
    13. Zhao X, Gu R, Zhao Y, Wei F, Gao X, Zhuang Y, Xiao Z, Shen H*, Dai J*. Adult spinal cord tissue transplantation combined with local tacrolimus sustained-release collagen hydrogel promotes complete spinal cord injury repair. Cell Prolif. 2023 May;56(5):e13451.
    14. Wang L, Feng M, Zhao Y, Chen B, Zhao Y*, Dai J*. Biomimetic scaffold-based stem cell transplantation promotes lung regeneration. Bioeng Transl Med. 2023 May 5;8(4):e10535.
    15. You Z, Gao X, Kang X, Yang W, Xiong T, Li Y, Wei F, Zhuang Y, Zhang T, Sun Y, Shen H*, Dai J*. Microvascular endothelial cells derived from spinal cord promote spinal cord injury repair. Bioact Mater. 2023 Jun 28;29:36-49.
    16. Fan Y, Wu X, Han S, Zhang Q, Sun Z, Chen B, Xue X, Zhang H, Chen Z, Yin M, Xiao Z*, Zhao Y*, Dai J*. Single-cell analysis reveals region-heterogeneous responses in rhesus monkey spinal cord with complete injury. Nat Commun. 2023 Aug 9;14(1):4796.
    17. Cui Y, Liu W, Zhao S, Zhao Y*, Dai J*. Advances in Microgravity Directed Tissue Engineering. Adv Healthc Mater. 2023 Sep;12(23):e2202768.
    18. Xiao Y, Zhang J, Tian Y, Zhang M, Du Y, Meng L, Liu Y, Zhang Z, Qiu L, Chen Y, Dong Q, Chen L, Gao J, Zheng J, Li Z, Li Q, Dai J*, Huang X*. Vaginal reconstruction with a double-sided biomembrane-a preclinical experimental study on large animals. Biomater Sci. 2023 Oct 24;11(21):7077-7089.
    19. Sun X, Xiong T, Yang K, Wang L, Yang W, Zhao H, Gao X, You Z, Zhuang Y, Chen Y*, Dai J*. Individually Tailored Modular "Egg" Hydrogels Capable of Spatiotemporally Controlled Drug Release for Spinal Cord Injury Repair. Adv Healthc Mater. 2023 Oct;12(27):e2301169.
    20. Fan C, He J, Xu S, Yan J*, Jin L*, Dai J*, Hu B*. Advances in biomaterial-based cardiac organoids. Biomater Adv. 2023 Oct;153:213502.
    21. Chen Z, Sun Z, Fan Y, Yin M, Jin C, Guo B, Yin Y, Quan R, Zhao S, Han S, Cheng X, Liu W, Chen B, Xiao Z, Dai J*, Zhao Y*. Mimicked Spinal Cord Fibers Trigger Axonal Regeneration and Remyelination after Injury. ACS Nano. 2023 Dec. 17(24):25591-25613
    22. Qu L, Chen Z, Chen J, Gan Y, Tan X, Wang Y, Zhang C, Chen B, Dai, J*, Chen J*, Shi C*. Collagen biomaterials promote the regenerative repair of abdominal wall defects in Bama miniature pigs. Biomater Sci. 2023 Dec 5;11(24):7926-7937.
    23. Wang Z, Li Y, Sun C, Cui P, Han Y, Wu T, Xu B, Zhang C*, Shi L*, Dai, J.* Locally controlled release of immunosuppressive promotes survival of transplanted adult spinal cord tissue. Regen Biomater. 2022 Dec 5;10:rbac097. 
    24. Kang X, Yang W, Gao X, Zhou L, Yu Z, Dong Q, Chen, Y*, Dai, J*, Zhang, H*. Biomimetic Janus Collagen Patch with Antideformation, Antiadhesion, and Prohealing Properties for Rehabilitation of Full-Layer Uterine Injuries, Toward Efficient Live Births; Advanced Materials Interfaces. 2023, 2300051
    25. Xiong T, Yang K, Zhao T, Zhao H, Gao X, You Z, Fan C, Kang X, Yang W, Zhuang Y, Chen Y*, Dai J.* Multifunctional Integrated Nanozymes Facilitate Spinal Cord Regeneration by Remodeling the Extrinsic Neural Environment. Adv Sci (Weinh). 2023 Mar;10(7):e2205997.
    26. Liu W, Xu B, Zhao S, Han S, Quan R, Liu W, Ji C, Chen B, Xiao Z, Yin M, Yin Y, Dai, J.* Zhao Y. *, Spinal cord tissue engineering via covalent interaction between biomaterials and cells. Sci Adv. 2023 Feb 10;9(6):eade8829.
    27. Wang X, Hou X, Zhao Y, Zhao R, Dai, J.* Dai H*, Wang C*. The early and late intervention effects of collagen-binding FGF2 on elastase-induced lung injury. Biomed Pharmacother. 2023 Feb;158:114147.
    28. Qian L, Yang K, Liu X, Zhang L, Zhao H, Qiu LZ, Chu Y, Hao W, Zhuang Y, Chen Y*, Dai, J.* Baicalein-functionalized collagen scaffolds direct neuronal differentiation toward enhancing spinal cord injury repair. Biomater Sci. 2023 Jan 17;11(2):678-689.
    29. Yang W, Kang X, Gao X, Zhuang Y, Fan C, Shen H, Chen Y*, Dai, J.* Biomimetic Natural Biopolymer-Based Wet-Tissue Adhesive for Tough Adhesion, Seamless Sealed, Emergency/Nonpressing Hemostasis, and Promoted Wound Healing. Adv. Funct. Mater. 2023, 33, 2211340.
    30. Gao X, You Z, Li Y, Kang X, Yang W, Wang H, Zhang T, Zhao X, Sun Y*, Shen H*, Dai, J.* Multifunctional hydrogel modulates the immune microenvironment to improve allogeneic spinal cord tissue survival for complete spinal cord injury repair  Acta Biomaterialia 2023 Jan 1;155:235-246.
    31. Wang Z, Li Y, Sun C, Cui P, Han Y, Wu T, Xu B, Zhang C*, Shi L*, Dai, J.* Locally controlled release of immunosuppressive promotes survival of transplanted adult spinal cord tissue. Regen Biomater. 2022 Dec 5;10:rbac097.
    32. Shu M, Hong D, Lin H, Zhang J, Luo Z, Du Y, Sun Z, Yin M, Yin Y, Liu L, Bao S, Liu Z, Lu F*, Huang J*, Dai, J.* Single-cell chromatin accessibility identifies enhancer networks driving gene expression during spinal cord development in mouse. Dev Cell. 2022 Dec 19;57(24):2761-2775.e6.
    33. Hong D, Lin H, Liu L, Dai J, Lu F, Tong M, Huang J*. Complexity of enhancer networks predicts cell identity and disease genes revealed by single-cell multi-omics analysis. Brief Bioinform. 2023 Jan 19;24(1):bbac508.
    34. Xu B, Yin M, Yang Y, Zou Y, Liu W, Qiao L, Zhang J, Wang Z, Wu Y, Shen H, Sun M, Liu W, Xue W, Fan Y, Zhang Q, Chen B, Wu X, Shi Y, Lu F, Zhao Y, Xiao Z, Dai, J.* Transplantation of neural stem progenitor cells from different sources for severe spinal cord injury repair in rat. Bioact Mater. 2022 Nov 23;23:300-313.
    35. Zhuang Y, Yang W, Zhang L, Fan C, Qiu L, Zhao Y, Chen B, Chen Y*, Shen H*, Dai, J.* A novel leptin receptor binding peptide tethered-collagen scaffold promotes lung injury repair. Biomaterials. 2022 Dec;291:121884.
    36. Liu X, Zhang L, Xu Z, Xiong X, Yu Y, Wu H, Qiao H, Zhong J, Zhao Z, Dai, J.*, Suo G. A functionalized collagen-I scaffold delivers microRNA 21-loaded exosomes for spinal cord injury repair. Acta Biomater. 2022 Dec;154:385-400.
    37. Ma D, Shen H, Chen F, Liu W, Zhao Y, Xiao Z, Wu X, Chen B, Lu J, Shao D, Dai, J.*. Inflammatory Microenvironment-Responsive Nanomaterials Promote Spinal Cord Injury Repair by Targeting IRF5. Adv Healthc Mater. 2022 Dec;11(23):e2201319.
    38. Jin C, Wu Y, Zhang H, Xu B, Liu W, Ji C, Li P, Chen Z, Chen B, Li J, Wu X, Jiang p, Hu Y, Xiao Z*, Zhao Y*, Dai, J.*. Spinal cord tissue engineering using human primary neural progenitor cells and astrocytes. Bioeng Transl Med. 2022;e10448. doi:10.1002/btm2.10448
    39. Jia W, Zhu H, Zhao M, Zhou Q, Yin W, Liu W, Wang L, Xiao Z, Jiang X, Dai, J.* Ren C*. Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells. Biochim Biophys Acta Mol Basis Dis. 2022 Nov 1;1868(11):166522.
    40. Fan C, Yang W, Zhang L, Cai H, Zhuang Y, Chen Y, Zhao Y, Dai, J.*. Restoration of spinal cord biophysical microenvironment for enhancing tissue repair by injury-responsive smart hydrogel. Biomaterials. 2022 Sep;288:121689.
    41. Cai J, Wang J, Sun C, Dai J, Zhang C. Biomaterials with stiffness gradient for interface tissue engineering. Biomed Mater. 2022 Sep 7;17(6).
    42. Zeng Y, Zhang C, Du D, Li Y, Sun L, Han Y, He X, Dai, J.* Shi L*.   Metal-organic framework-based hydrogel with structurally dynamic properties as a stimuli-responsive localized drug delivery system for cancer therapy.   Acta Biomater.   2022 Jun;145:43-51.
    43. Tang F, Tang J, Zhao Y, Zhang J, Xiao Z, Chen B, Han G, Yin N, Jiang X, Zhao C, Cheng S, Wang Z, Chen Y, Chen Q, Song K, Zhang Z, Niu J, Wang L, Shi Q, Chen L, Yang H, Hou S, Zhang S, Dai, J.*. Long-term clinical observation of patients with acute and chronic complete spinal cord injury after transplantation of NeuroRegen scaffold. Sci China Life Sci. 2022 May;65(5):909-926
    44. Jin X, Liu W, Wang J, Xiao Z, Niu Y, Chen B, Zhao Y, Dai, J.* Clinical study of injectable collagen scaffold with autologous fat cells for repair of severe vocal fold injury. Biomed Mater. 2022 Apr 12;17(3).
    45. Xue X, Shu M, Xiao Z, Zhao Y, Li X, Zhang H, Fan Y, Wu X, Chen B, Xu B, Yang Y, Liu W, Liu S, Dai, J.*. Lineage tracing reveals the origin of Nestin-positive cells are heterogeneous and rarely from ependymal cells after spinal cord injury. Sci China Life Sci. 2022 Apr;65(4):757-769.
    46. Zhou Z, Wang H, Zhang X, Song M, Yao S, Jiang P, Liu D, Wang Z, Lv H, Li R, Hong Y, Dai, J.* Hu Y*, Zhao G*. Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions. Autophagy. 2022 Feb 23:1-16.
    47. Han Y, Sun L, Wen C, Wang Z*, Dai, J.*, Shi L*. Flexible conductive silk-PPy hydrogel toward wearable electronic strain sensors.   Biomed Mater. 2022 Feb 21;17(2).
    48. Lv H, Zhao G, Jiang P, Wang H, Wang Z, Yao S, Zhou Z, Wang L, Liu D, Deng W, Dai, J.*, Hu Y*. Deciphering the endometrial niche of human thin endometrium at single-cell resolution.   Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2115912119.
    49. Zou Y, Yin Y, Xiao Z, Zhao Y, Han J, Chen B, Xu B, Cui Y, Ma X, Dai, J.*. Transplantation of collagen sponge-based three-dimensional neural stem cells cultured in a RCCS facilitates locomotor functional recovery in spinal cord injury animals. Biomater Sci. 2022 Feb 15;10(4):915-924.
    50. Yin Z, Sun L, Shi L, Nie H, Dai, J.*, Zhang C*. Bioinspired bimodal micro-nanofibrous scaffolds promote the tenogenic differentiation of tendon stem/progenitor cells for achilles tendon regeneration. Biomater Sci. 2022 Feb 1;10(3):753-769.
    51. Zhao X, Wang H, Zou Y, Xue W, Zhuang Y, Gu R, Shen H, Dai, J.* Optimized, visible light-induced crosslinkable hybrid gelatin/hyaluronic acid scaffold promotes complete spinal cord injury repair. Biomed Mater. 2022 Jan 25;17(2).
    52. Chen Z, Zhang H, Fan C, Zhuang Y, Yang W, Chen Y, Shen H, Xiao Z, Zhao Y*, Li X*, Dai, J.* Adhesive, Stretchable, and Spatiotemporal Delivery Fibrous Hydrogels Harness Endogenous Neural Stem/Progenitor Cells for Spinal Cord Injury Repair. ACS Nano. 2022 Feb 22;16(2):1986-1998.
    53. Shen H, Xu B, Yang C, Xue W, You Z, Wu X, Ma D, Shao D, Leong K, Dai, J.*A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury. Biomaterials. 2022 Jan;280:121279.
    54. Shen, H., Fan, C., You, Z., Xiao, Z., Zhao, Y*., Dai, J.* (2021). Advances in Biomaterial‐Based Spinal Cord Injury Repair. Advanced Functional Materials, 2110628.
    55. Yu Y, Liu X, Zhao Z, Xu Z, Qiao Y, Zhou Y, Qiao H, Zhong J, Dai J, Suo G*. The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice. Front Pharmacol. 2021 Dec 6;12:747223. doi: 10.3389/fphar.2021.747223.
    56. Wang H, Zhu C, Xu Z, Wei X, Shen H, Wang L, Wang B, Chen B, Zhao Y, Yu C, Dai, J.* Gao X. Clinical application of collagen membrane with umbilical cord-derived mesenchymal stem cells to repair nasal septal perforation. Biomed Mater. 2021 Nov 11;17(1).
    57. Zhang Q, Wu X, Fan Y, Jiang P, Zhao Y, Yang Y, Han S, Xu B, Chen B, Han J, Sun M, Zhao G, Xiao Z, Hu Y, Dai, J.* Single-cell analysis reveals dynamic changes of neural cells in developing human spinal cord. EMBO Rep. 2021 Nov 4;22(11):e52728 doi: 10.15252/embr.202152728
    58. Chu Y, Huang L, Hao W, Zhao T, Zhao H, Yang W, Xie X, Qian L, Chen Y, Dai, J.* Long-term stability, high strength, and 3D printable alginate hydrogel for cartilage tissue engineering application. Biomed Mater. 2021 Sep 28;16(6). doi: 10.1088/1748-605X/ac2595
    59. Tang F, Tang J, Zhao Y, Zhang J, Xiao Z, Chen B, Han G, Yin N, Jiang X, Zhao C, Cheng S, Wang Z, Chen Y, Chen Q, Song K, Zhang Z, Niu J, Wang L, Shi Q, Chen L, Yang H, Hou S, Zhang S, Dai, J.*. Long-term clinical observation of patients with acute and chronic complete spinal cord injury after transplantation of NeuroRegen scaffold. Sci China Life Sci. 2021 Aug 16. doi: 10.1007/s11427-021-1985-5.
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