--中国科学院遗传与发育生物学研究所

姓　　名：	傅向东
职　　称：	研究员
职　　务：	副所长（主持工作），种子创新全国重点实验室主任
电话/传真：	86-10-64806558
电子邮件：	xdfu@genetics.ac.cn
实验室主页：
研究方向：	植物发育和环境适应的激素调控机理

简历介绍：

傅向东，博士，研究员，博士生导师, 中国科学院大学岗位教授，中国科学院院士

学习经历

1987-1991，武汉大学生物系遗传学专业，学士

1991-1994，中国科学院武汉植物所植物学专业，硕士

1998-2001，英国John Innes Centre和浙江大学联合培养农学专业，博士

工作经历

1994-1996，浙江农业大学生物技术研究所，助理研究员

1996-1997，英国John Innes Centre，访问学者

1997-1998，浙江大学生物技术研究所，讲师

2001-2005，英国John Innes Centre，博士后

2005至今，中国科学院遗传与发育生物学研究所，研究员

2015至今，中国科学院大学，岗位教授

学术和社会任职

2024-今，中国植物生理与植物分子生物学学会第十三届理事会理事

2019-今，中国植物生理与植物分子生物学学会遗传与分子生物学专业委员会主任

2023-今，中国植物学会第十七届理事会理事

2024-今，中国作物学会副理事长

2024-今，中国遗传学会第十一届理事会理事

2022-今，Plant Physiology编委

2022-今，Advanced Genetics顾问编委

2024-今，Frontiers in Plant Science编委

2014-今，Journal of Genetics and Genomics编委

2022-今，aBIOTECH编委

2022-今，生物工程学报编委

2021-今，植物学报责任编委

2021-今，生命科学编委

荣誉奖励

2025年，当选中国科学院院士

2023年，北京学者

2023年，神农领军英才

2023年，全国创新争先奖（个人奖）

2023年，中国科学院优秀共产党员

2022年，新基石研究员

2022年，中国科学院杰出科技成就奖（突出贡献者）

2021年，中国科学院大学“领雁”银奖

2020年，国家自然科学奖二等奖（第一完成人）

2020年，第八届“中国侨届贡献奖”一等奖

2019年，中国科学院遗传发育所“建所60年杰出贡献奖”

2019年，中国科学院优秀导师奖

2017年，第十届“谈家桢生命科学创新奖”

2014年，科技部创新人才推进计划中青年科技创新领军人才

2014年，全国优秀科技工作者

2013年，“第八届大北农科技奖”一等奖

2012年，中国科学院“朱李月华优秀教师”奖

2011年，中国科学院优秀导师奖

2010年，“第十一届中国青年科技奖”

2009年，国务院“享受政府特殊津贴专家”

2005年，国家自然科学基金委“杰出青年基金”

研究领域：

研究方向

1. 植物激素与环境互作调控植物生长-代谢的耦合机制：植物的生长发育受内源激素（如赤霉素、生长素等）和可变环境（如光、土壤氮水平等）的共同影响。系统解析赤霉素与其他植物激素、光和氮营养等互作调控植物生长发育与碳氮代谢适应环境变化的复杂分子网络和分子机制。

DELLA-GRF4分子模块调控植物生长-代谢平衡，实现“绿色革命”品种减肥增效（Nature,2018）

入选2018年度中国科学十大进展、2019年度中国农业科学十大进展

DELLA-NGR5协同提高水稻产量和氮利用效率的表观遗传新机制（Science,2020）

入选2020年度中国生命科学十大进展、2021年度中国农业科学十大进展

RCN2-DELLA-SPL14分子模块精准调控染色质三维结构实现水稻可持续高产（Nature Genetics,2025）

2. 农作物优质、高产和氮高效协同改良的遗传调控网络解析与设计育种：针对当前我国水稻育种面临的周期长、效率低、品种同质化严重、绿色优质高产多个优良性状难以兼顾等技术瓶颈，布局“基因挖掘-功能验证-基因聚合-品种设计”一体化技术创新链，挖掘高产、优质、氮高效关键核心基因，解析水稻优质、高产和氮高效协同改良的遗传调控网络，为打破“优质不高产”、“高产不高效”育种瓶颈提供多模块组装的品种设计新策略；采用精准的科企合作模式，利用分子设计育种理念，聚合多个优质、高产、氮高效基因，培育绿色优质高产水稻新品种。

“中禾优”系列国审水稻新品种

社会任职：

获奖及荣誉：

承担科研项目情况：

代表论著：

代表性论文

1. Liu Q^#,Liu H^#,Sun L^#,Wang D^#,Sun X,Wu K,Ye Y,Wang Y,Wang S,Zhong N,Wu X,Li Y,Deng M,Wang M,Wu C,Liu X,Zhang Y,Xiao J,Wu Y,Fu X* (2025 ) Precise control of chromatin loop extrusion enhances sustainable green revolution yield in rice. Nature Genetics 57,2798-2807.

2. Hu J,Liu H,Gao X,Fu X(2025)Reprogrammable design of DELLA as a strategy to mitigate alkaline-heat stress for sustainable agriculture. Molecular Plant 18,744-746.

3. Zhang H^#,Liu M^#,Lou S^#,Han Y,Liu B,Yang S,Feng X,Feng L,Lin H,Zheng Y,Song Y,Yan J,Hou J,Gao X,Gu S,Yao Y,Guo X,Liu X,Liang R,Guo M,Liu J*,Fu X*,Liu H* (2025) Allelic variations and interactive feedback in major regulators of plant architecture confer high-altitude adaptation in Arabidopsis thaliana. New Phytologist 248: 2964-2980.

4. Xiao S,Song W,Wang R,Zhang S,Liu M,Zhang R,Xu T,Liu H,Hu J,Xing J,Wang X,Wang T,Fu X* ,Zhao J * (2025) Reinventing a sustainable Green Revolution by breeding and planting semi-dwarf maize. Molecular Plant 18,1626-1642.

5. Wang Z,Miao L,Tan K,Guo W,Xin B,Appels R,Jia J,Lai J,Lu F*,Ni Z*,Fu X*,Sun Q*,Chen J* (2025) Near-complete assembly and comprehensive annotation of the wheat Chinese Spring genome. Molecular Plant 18,892-907

6. Liu H,Gao X,Fan W*,Fu X* (2025) Optimizing carbon and nitrogen metabolism in plants: From fundamental principles to practical applications. Journal of Integrative Plant Biology 67: 1447-1466.

7. Wang S,Hu J,Song W,Zhang Q,Wu C,Zhou J,Yang L,Wu Y,Ye Y,Fan W,Fu X*,Wu K* (2025) Design strategies for enhanced sustainable green revolutionproductivity in rice. Journal of Genetics and Genomics,https://doi.org/10.1016/j.jgg.2025.06.004.

8. Guan H,Chen Z,Wang S,Jiang B,Zhao J,Gao Y,Zhu S,Li S,Mao D,Lin L,Fan W,Liu Q,Song W,Huang L,Xie X,Wan C,Ye Y,Cheng S,Chu J,Fu X*,Wu W*,Wu K*(2025) An elite RNA-DEPENDENT RNA POLYMERASE3 allele enhances preharvest sprouting resistance in rice. Plant Physiology 198.

9. Liu H,Fu X (2024) Phytohormonal networks facilitate plant root developmental adaptations to environmental changes. Science Bulletin 69 (2024) 709-713.

10. Wu Y,Zhao Y,Yu J,Wu C,Wang Q,Liu X,Gao X,Wu K,Fu X*,Liu Q* (2023) Heterotrimeric G protein g subunit DEP1 synergistically regulates grain quality and yield by modulating the TTP (TON1-TRM-PP2A) complex in rice. Journal of Genetics and Genomics 50,528e531.

11. Kong X^#,Wang F^#,Wang Z^#,Gao X^#,Geng S,Deng Z,Zhang S,Fu M,Cui D,Liu S,Che Y,Liao R,Yin L,Zhou P,Wang K,Ye X,Liu D,Fu X*,Mao L*,Li A* (2023) Grain yield improvement by genome editing of TaARF12 that decoupled peduncle and rachis development trajectories via differential regulation of gibberellin signalling in wheat. Plant Biotechnology Journal 21,1990-2001.

12. Ren Y^#,Liu B^#,Jiang H,Cheng W,Tao L,Wu K,Wang H,Shen G,Fang Y,Zhang C,Wu Y*, Fu X*,Ye Y* (2023) Precision editing of GLR1 confers glufosinate resistance without yield penalty in rice. Plant Biotechnology Journal,1-3.

13. Sun H,Guo X,Zhu X,Gu P,Zhang W,Tao W,Wang D,Wu Y,Zhao Q,Xu G,Fu X*,Zhang Y* (2023) Strigolactone and gibberellin signaling coordinately regulate metabolic adaptations to changes in nitrogen availability in rice. Molecular Plant 16,588-598.

14. Liu Q,Wu K,Wu Y,Song W,Wang S,Fu X* (2022) Beyond the Green Revolution: Improving crop productivity and sustainability by modulating plant growth-metabolic coordination. Molecular Plant 15,573-576.

15. Liu Q,Wu K,Song W,Zhong N,Wu Y, Fu X* (2022) Improving Crop Nitrogen Use Efficiency Toward Sustainable Green Revolution. Annual Review of Plant Biology 73: 523-551.

16. Li A^#*,Hao C^#,Wang Z^#,Geng S,Jia M,Wang F,Han X,Kong X,Yin L,Tao S,Deng Z,Liao R,Sun G,Wang K,Ye X,Jiao C,Lu H,Zhou Y,Liu D,Fu X*,Zhang X* and Mao Long* (2022) Wheat breeding history reveals synergistic selection of pleiotropic genomic sites for plant architecture and grain yield. Molecular Plant 15,504-519.

17. Wu K,Xu H,Gao X,Fu X* (2021) New insights into gibberellin signaling in regulating plant growth-metabolic coordination. Current Opinion in Plant Biology 63,102074.

18. Liu Q,Wu K,Harberd NP,Fu X* (2021) Green Revolution DELLAs: From translational reinitiation to future sustainable agriculture. Molecular Plant 14(4),547-549.

19. Wu K^#,Wang S^#,Song W,Zhang J,Wang Y,Liu Q,Yu J,Ye Y,Li S,Chen J,Zhao Y,Wang J,Wu X,Wang M,Zhang Y,Liu B,Wu Y,Harberd NP*, Fu X* (2020) Enhanced sustainable green revolution yield via nitrogen-responsive chromatin modulation in rice. Science 367 (6478).

20. Xu X^#,Wu K^#,Xu R,Wang S,Gao Z,Zhong Y,Li X,Liao H,Fu X* (2019) Pyramiding of the dep1-1 and NAL1^NJ6 alleles achieves sustainable improvements in nitrogen-use efficiency and grain yield in japonica rice breeding. Journal of Genetics and Genomics 46(6),325-328.

21. Li S,Tian Y,Wu K,Ye Y,Yu J,Zhang J,Liu Q,Hu M,Li H,Tong Y,Harberd NP,Fu X* (2018) Modulating plant growth-metabolism coordination for sustainable agriculture. Nature 520 (7720),595-600.

22. Liu Q^#,Han R^#,Wu K,Zhang J,Ye Y,Wang S,Chen J,Pan Y,Li Q,Xu X,Zhou J,Tao D,Wu Y,Fu X* (2018) G-protein βγ subunits determine grain size through interaction with MADS-domain transcription factors in rice. Nature Communications 9,852.

23. Wu K^#,Xu X^#,Zhong N,Huang H,Yu J,Ye Y,Wu Y,Fu X* (2018) The rational design of multiple molecular module-based assemblies for simultaneously improving rice yield and grain quality. Journal of Genetics and Genomics 45(6),337-341.

24. Ye Y,Wu K,Chen J,Liu Q,Wu Y,Liu B*,Fu X* (2018) OsSND2,a NAC family transcription factor,is involved in secondary cell wall biosynthesis through regulating MYBs expression in rice. Rice 11,36.

25. Wang S^#,Wu K^#,Qian Q^#,Qian L,Pan Y,Ye Y,Liu X,Wang J,Zhang J,Li S,Wu Y,Fu X* (2017) Non-canonical regulation of SPL transcription factors by a human OTUB1-like deubiquitinase defines a new plant type rice associated with higher grain yield. Cell Research 27(9),1142-1156.

26. Chen X,Yao Q,Gao X,Jiang C,Harberd NP,Fu X* (2016) Shoot-to-Root mobile transcription factor HY5 coordinates plant carbon and nitrogen acquisition. Current Biology 26,640-646.

27. Liu Q,Harberd NP,Fu X* (2016) SQUAMOSA Promoter Binding Protein-like Transcription Factors: Targets for Improving Cereal Grain Yield. Molecular Plant 9,765-767.

28. Liu Q,Chen X,Wu K,Fu X* (2015) Nitrogen signaling and use efficiency in plants: what’s new?Current Opinion in Plant Biology 27,192-198.

29. Wang S,Li S,Liu Q,Wu K,Zhang J,Wang S,Wang Y,Chen X,Zhang Y,Gao C,Wang F,Huang H,Fu X* (2015) The OsSPL16-GW7 regulatory module determines grain shape and simultaneously improves rice yield and grain quality. Nature Genetics 47(8),949-954.

30. Ye Y,Liu B,Zhao M,Wu K,Cheng W,Chen X,Liu Q,Liu Z,Fu X*,Wu Y* (2015) CEF1/OsMYB103L is involved in GA-mediated regulation of secondary wall biosynthesis in rice. Plant Molecular Biology 89(4-5),385-401.

31. Xu H,Liu Q,Yao T,Fu X* (2014) Shedding light on integrative GA signaling. Current Opinion in Plant Biology 21,89-95.

32. Sun H^#,Qian Q^#,Wu K^#,Luo J^#,Wang S^#,Zhang C,Ma Y,Liu Q,Huang X,Yuan Q,Han R,Zhao M,Dong G,Guo L,Zhu X,Gou Z,Wang W,Wu Y,Lin H,Fu X* (2014) Heterotrimeric G proteins regulate nitrogen-use efficiency in rice. Nature Genetics 46,652-656.

33. Ma W,Li J,Qu B,He X,Zhao X,Li B,Fu X*,Tong Y* (2014) Auxin biosynthetic gene TAR2 is involved in low nitrogen mediated reprogramming of root architecture in Arabidopsis. Plant Journal 78,70-79.

34. Wang S,Wu K,Yuan Q,Liu X,Liu Z,Lin X,Zeng R,Zhu H,Dong G,Qian Q,Zhang G *,Fu X* (2012) Control of grain size,shape and quality by OsSPL16 in rice. Nature Genetics 44,950-954.

35. Gao X,Xiao S,Yao Q,Wang Y,Fu X* (2011) An Updated GA Signaling’Relief of Repression’Regulatory Model. Molecular Plant 4,60-606.

36. Wu J,Kong X,Wan J,Liu X,Zhang X,Guo X,Zhou R,Zhao G,Jing R,Fu X*,Jia J* (2011) Dominant and Pleiotropic Effects of a GAI Gene in Wheat Results from a Lack of Interaction between DELLA and GID1. Plant Physiology 157,2120-2130.

37. Huang X^#,Qian Q^#,Liu Z,Sun H,He S,Luo D,Xia G,Chu C,Li J,Fu X* (2009) Natural variation at the DEP1 locus enhances grain yield in rice. Nature Genetics 41,494-497.

38. Jiang C,Gao X,Liao L,Harberd NP, Fu X* (2007) Phosphate-starvation root architecture and anthocyanin accumulation responses are modulated by the GA-DELLA signaling pathway in Arabidopsis. Plant Physiology 145,1460-1470.

39. Jiang C,Fu X* (2007) GA action: turning on de-DELLA repressing signaling. Current Opinion in Plant Biology 10,461-465.