代表性论文:(*通讯作者)
1. Luo X, Dai M, Wang M, Wang X, Guo W*. Functional heterogeneity of Wnt-responsive and Hedgehog-responsive neural stem cells in the murine adult hippocampus. Dev Cell. 2023; DIO: 10.1016/j.devcel.2023.07.021.
2. Xu M, Guo Y, Wang M, Luo X, Shen X, Li Z, Wang L, Guo W*. L-arginine homeostasis governs adult neural stem cell activation by modulating energy metabolism in vivo. EMBO J. 2023; 42: e112647.
3. Liu Y, Wang M, Guo Y, Wang L, Guo W*. D-2-hydroxyglutarate dehydrogenase governs adult neural stem cell activation and promotes histone acetylation via ATP-citrate lyase. Cell Rep. 2023; 42(2):112067.
4. Guo Y, Wu J, Wang M, Wang X, Jian Y, Yang C, Guo W*. The metabolite saccharopine impairs neuronal development by inhibiting the neurotrophic function of glucose-6-phosphate isomerase. J Neurosci. 2022; 42(13):2631-2646. (Featured Research)
5. Han X, Shen X, Wang M, Wang X, Jian Y, Yang C, Guo W*. Loss of RNA-Binding Protein HuR Leads to Defective Ependymal Cells and Hydrocephalus. J Neurosci. 2022; 42(2):202-219.
6. Xing R, Zhou H, Jian Y, Li L, Wang M, Liu N, Yin Q, Liang Z, Guo W*, Yang C*. The Rab7 effector WDR91 promotes autophagy-lysosome degradation in neurons by regulating lysosome fusion. J. Cell Biol. 2021; 220(8):e202007061.
7. Zhang B, Wang L, Zhan A, Wang M, Tian L*, Guo W*, Pan Y. Long-term exposure to a hypomagenetic field attenuates adult hippocampal neurogenesis and cognition. Nat. Commun. 2021; 12 (1):1174. (Featured Article)
8. Wang M, Tang C, Xing R, Liu X, Han X, Liu Y, Wang L, Yang C*, Guo W*. WDR81 regulates adult hippocampal neurogenesis through endosomal SARA-TGFβ signaling. Mol. Psychiatry. 2021; 26(2):694-709.
9. Zhao Y, He X, Song Z, Guo Y, Zhang Y, Yu H, He Z, Xiong W, Guo W*, Zhu X*. Human antigen R-regulated mRNA metabolism promotes the cell motility of migrating neurons. Development. 2020. 147 (6):dev183509.
10.Wang Y, Guo Y, Tang C, Han X, Xu M, Sun J, Zhao Y, Zhang Y, Wang M, Cao X, Zhu X, Guo W*. Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis. Cell Rep. 2019. 29 (10): 3101-3117.
11.Wang J, Cui Y, Yu Z, Wang W, Cheng X, Ji W, Guo S, Zhou Q, Wu N, Chen Y, Chen Y, Song X, Jiang H, Wang Y, Lan Y, Zhou B, Mao L, Li J, Yang H*, Guo W*, Yang X*. Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis. Cell Stem Cell. 2019. 25(6):754-767.
(Preview: Sensing the Environment: Extracellular Lactate Levels Control Adult Neurogenesis. Scandella V. and Knobloch M. 2019. Cell Stem Cell. 25(6):729-731)
12.Zhou J, Wang X, Wang M, Chang Y, Zhang F, Ban Z, Tang R, Gan Q, Wu S, Guo Y, Zhang Q, Wang F, Zhao L, Jing Y, Qian W, Wang G, Guo W*, Yang C*. The lysine catabolite saccharopine impairs development by disrupting mitochondrial homeostasis. J. Cell Biol. 2019; 218(2):580-597.
(Spotlight: Saccharopine, a lysine degradation intermediate, is a mitochondrial toxin. Leandro J. and Houten SM. 2019; J. Cell Biol. 2018(2):391-392.)
13.Tang C, Wang M, Wang P, Wang L, Wu Q, Guo W*. Neural Stem Cells Behave as a Functional Niche for the Maturation of Newborn Neurons through the Secretion of PTN. Neuron. 2019; 101(1):32-44.
(Preview: Interactive Regulation of Neuronal Development by Hippocampal Stem Cell Niche Populations. LeBelle J. and Kornblum H. 2019. Neuron. 101(1):1-2.)
14.Liu K, Xing R, Jian Y, Gao Z, Ma X, Sun X, Li Y, Xu M, Wang X, Jing Y, Guo W*, Yang C*, WDR91 is a Rab7 effector required for neuronal development. J. Cell Biol. 2017; 216(10):3307-3321.
(Spotlight: A new Rab7 effector controls phosphoinositide conversion in endosome maturation. Casanova J. and Winckler B. 2017. J. Cell Biol. 216(10): 2995-2997)
15.Liu X, Yang Li, Wang X, Xing R, Liu K, Gan Q, Tang C, Gao Z, Jian Y, Luo S, Guo W*, Yang C*, The Beach-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy. J. Cell Biol. 2017; 216(5):1301-1320.
16.Wang F, Tidei JJ, Polich ED, Gao Y, Zhao H, Perrone-Bizzozero NI*, Guo W*, Zhao X*. Positive feedback between RNA-binding protein HuD and transcription factor SATB1 promotes neurogenesis. Proc. Natl. Acad. Sci. U S A. 2015; 112(36):E4995-5004.