姓  名: 段力辉
    职  称: 研究员
    职  务:
    电话/传真: 86-10-64806596
    电子邮件: lihui.duan@genetics.ac.cn
    实验室主页:
    研究方向: 成纤维细胞在神经系统发育和神经免疫中的功能

    简历介绍:

    段力辉,博士,研究员,博士生导师
     
            2010年在华中农业大学生物学基地班获得理学学士学位;2018年在中国科学院神经所获得博士学位;2018年至2022年在加州大学旧金山分校从事博士后研究工作;2022年加入中国科学院遗传与发育生物学研究所任研究员。

    研究领域:

    主要研究方向:
            1. 大脑成纤维细胞的发育分化
            2. 成纤维细胞与神经系统的直接相互作用
            3. 成纤维细胞如何通过招募免疫细胞间接调控神经系统

    社会任职:

    获奖及荣誉:

    承担科研项目情况:

    代表论著:

    发表文章:
      

    Wolf, E.W., Howard, Z.P., Duan, L., Tam, H., Xu, Y., and Cyster, J.G. (2022). GPR174 signals via G α s to control a CD86-containing gene expression program in B cells. Proceedings of the National Academy of Sciences 119, e2201794119.
     
    Liu, D., Duan, L., and Cyster, J.G. (2022a). Chemo‐and mechanosensing by dendritic cells facilitate antigen surveillance in the spleen. Immunological Reviews 306, 25-42.
     
    Liu, D., Duan, L., Rodda, L.B., Lu, E., Xu, Y., An, J., Qiu, L., Liu, F., Looney, M.R., and Yang, Z. (2022b). CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells. Science 375, eabi5965.
     
    Duan, L.*, Liu, D.*, Chen, H., Mintz, M.A., Chou, M.Y., Kotov, D.I., Xu, Y., An, J., Laidlaw, B.J., and Cyster, J.G. (2021). Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation. Immunity 54, 2256-2272. e2256. (Highlighted by Nature Immunology)
     
    Laidlaw, B.J., Duan, L., Xu, Y., Vazquez, S.E., and Cyster, J.G. (2020). The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development. Nature immunology 21, 1082-1093.
     
    Duan, L.*, Zhang, X.-D.*, Miao, W.-Y., Sun, Y.-J., Xiong, G., Wu, Q., Li, G., Yang, P., Yu, H., and Li, H. (2018). PDGFRβ cells rapidly relay inflammatory signal from the circulatory system to neurons via chemokine CCL2. Neuron 100, 183-200. e188. (Preview highlight on Neuron)
     
    Zhang, S.-X.*, Duan, L.*, He, S.-J., Zhuang, G.-F., and Yu, X. (2017). Phosphatidylinositol 3, 4-bisphosphate regulates neurite initiation and dendrite morphogenesis via actin aggregation. Cell research 27, 253-273.
     
    Zhang, S.-X.*, Duan, L.*, Qian, H., and Yu, X. (2016). Actin aggregations mark the sites of neurite initiation. Neuroscience bulletin 32, 1-15.
     
    翻译书籍:
       OpenCV-python中文教程
       R语言数据挖掘
       高级R语言编程指南