姓  名: 宋显伟
    职  称: 青年研究员
    职  务:
    电话/传真: 010-64806632
    电子邮件: xwsong@genetics.ac.cn
    实验室主页:
    研究方向: 植物表观遗传学与抗逆

    简历介绍:

    宋显伟,博士,青年研究员
    学习经历:(从大学开始)
        1999 - 2003     东北师范大学,学士
        2003 - 2006     东北师范大学,硕士
        2006 - 2011     中科院遗传与发育生物学研究所,博士
    工作经历
         2011 - 2016   中科院遗传与发育生物学研究所,助理研究员
         2017 - 2019   中科院遗传与发育生物学研究所,副研究员
         2020 - 今      中科院遗传与发育生物学研究所,青年研究员

    研究领域:

    研究内容:
        1. 植物响应温度和盐碱胁迫的遗传和表观遗传机理研究
        2. 牧草育种和边际土地的生物改良

    获得奖励:
        2015年   北京市科学技术二等奖(第三完成人)
        2019年   国家自然科学奖二等奖(第三完成人)

    社会任职:

    获奖及荣誉:

    承担科研项目情况:

    代表论著:

    代表论著:
    2) Cuimei Zhang#, Yajun Tang#, Shanjie Tang#, Lei Chen, Haidi Yuan, Yujun Xu, Yangyan Zhou, Shuaibin Zhang, Jianli Wang, Hongyu Wen, Wenbo Jiang, Yongzhen Pang, Xian Deng, Xiaofeng Cao, Junhui Zhou*, Xianwei Song*, Qikun Liu*. An Inducible CRISPR-activation tool for accelerated plant regeneration. Plant Communications.5(5), 1-14, 2024
    3) Xiangyan Han#, Shanjie Tang#, Xuan Ma, Wenwen Liu, Ruijuan Yang, Shuaibin Zhang, Ningning Wang, Xianwei Song, Chunxiang Fu*, Rongxin Yang*, Xiaofeng Cao*. Blocking miR528 function promotes tillering and regrowth in switchgrass. Plant Biotechnology Journal, 22(3), 712-721, 2024
    4) Mingxing Wang#, An-Hui Ge#, Xingzhu Ma#, Xiaolin Wang, Qiujin Xie, Like Wang, Xianwei Song, Mengchen Jiang, Weibing Yang, Jeremy D Murray, Yayu Wang, Huan Liu, Xiaofeng Cao*, Ertao Wang*. Dynamic root microbiome sustains soybean productivity under unbalanced fertilization. Nature Communications, 15(1), 1168, 2024
    5) Han Hu#, Ji Chen#, Feng Zhou, Ming Nie, Deyi Hou, Huan Liu, Manuel Delgado-Baquerizo, Haowei Ni, Weigen Huang, Jizhong Zhou, Xianwei Song, Xiaofeng Cao, Bo Sun, Jiabao Zhang, Thomas W Crowther, Yuting Liang*. Relative increases in CH4 and CO2 emissions from wetlands under global warming dependent on soil carbon substrates. Nature Geoscience, 17(1), 26-31, 2024
    6) Haofei Luo#, Xiaofei Wang#, Changqing You#, Xuedan Wu#, Duofeng Pan#, Zhiyao Lv#, Tong Li, Dongmei Zhang, Zhongbao Shen, Guodao Liu, Kaixuan He, Qingtong Ye, Yajun Jia, Qinghua Zhao, Xian Deng, Xiaofeng Cao*, Xianwei Song*, Gai Huang*. Telomere-to-telomere genome of the allotetraploid legume Sesbania cannabina reveals transposon-driven subgenome divergence and mechanisms of alkaline stress tolerance. Science China Life Sciences, 67(1), 149-160, 2024
    7) Tong Li#, Shanjie Tang#, Wei Li#, Shuaibin Zhang, Jianli Wang, Duofeng Pan, Zhelong Lin, Xuan Ma, Yanan Chang, Bo Liu, Jing Sun, Xiaofei Wang, Mengjie Zhao, Changqing You, Haofei Luo, Meijia Wang, Xingguo Ye, Jixian Zhai, Zhongbao Shen, Huilong Du*, Xianwei Song*, Gai Huang*, Xiaofeng Cao*. Genome evolution and initial breeding of the Triticeae grass Leymus chinensis dominating the Eurasian Steppe. Proceedings of the National Academy of Sciences of the United States of America, 120(44), 1-10, 2023
    8) Xiaofeng Zu#, Lilan Luo#, Zhen Wang#, Jie Gong, Chao Yang, Yong Wang, Chunhui Xu, Xinhua Qiao, Xian Deng, Xianwei Song, Chang Chen, Bao-Cai Tan & Xiaofeng Cao*. A mitochondrial pentatricopeptide repeat protein enhances cold tolerance by modulating mitochondrial superoxide in rice. Nature Communications, 14, 6189, 2023
    9) Zhelong Lin#, Lei Chen#, Shanjie Tang, Mengjie Zhao,Tong Li, Jia You, Changqing You, Boshu Li, Qinghua Zhao, Dongmei Zhang, Jianli Wang, Zhongbao Shen, Xianwei Song, Shuaibin Zhang* and Xiaofeng Cao*. Efficient CRISPR/Cas9‐mediated genome editing in sheepgrass (Leymus chinensis). Journal of Integrative Plant Biology, 65(11), 2416-2420, 2023
    10) Xueting Gu#. Fuyan Si#, Zhengxiang Feng#, Shunjie Li#, Di Liang#, Pei Yang, Chao Yang, Bin Yan, Jun Tang, Yu Yang, Tai Li, Lin Li, Jinling Zhou, Ji Li, Lili Feng, Ji-Yun Liu, Yuanzhu Yang, Yiwen Deng, Xuna Wu, Zhigang Zhao, Jianmin Wan, Xiaofeng Cao, Xianwei Song*, Zuhua He*, Junzhong Liu*. The OsSGS3-tasiRNA-OsARF3 module orchestrates abiotic-biotic stress response trade-off in rice. Nature Communications, 14, 4441, 2023
    11) Zhijian Liu#, Xiangying Kong#, Yanping Long#, Sirui Liu, Hong Zhang, Jinbu Jia, Wenhui Cui, Zunmian Zhang, Xianwei Song, Lijuan Qiu, Jixian Zhai* & Zhe Yan*. Integrated single-nucleus and spatial transcriptomics captures transitional states in soybean nodule maturation. Nature Plants, 9, 515-524, 2023
    12) Fuyan Si#, Haofei Luo#, Chao Yang#, Jie Gong, Bin Yan, Chunyan Liu, Xianwei Song* and Xiaofeng Cao*. Mobile ARGONAUTE 1d binds 22-nt miRNAs to generate phasiRNAs important for low-temperature male fertility in rice. Science China Life Sciences, 66, 197-208, 2023 (Cover story)
    13) Zhen Wang#, Jing Sun#, Xiaofeng Zu#, Jie Gong#, Hongjing Deng, Runlai Hang, Xiaofan Zhang, Chunyan Liu, Xian Deng, Lilan Luo, Xiangjin Wei*, Xianwei Song* and Xiaofeng Cao*. Pseudouridylation of chloroplast ribosomal RNA contributes to low temperature acclimation in rice. New Phytologist, 236(5), 1708-1720, 2022
    14) Fuyan Si#, Chao Yang#, Bin Yan, Wei Yan, Shanjie Tang, Yan Yan, Xiaofeng Cao*, Xianwei Song*. Control of OsARF3a by OsKANADI1 contributes to lemma development in rice. The Plant Journal, (7), 1717-1730, 2022
    15) Wei Liu#, Jing Sun#, Chunyan Liu, Fuyan Si, Zhen Wang, Xianwei Song, Yuanzhu Yang, Yuxian Zhu*, Xiaofeng Cao*. Reproductive tissue-specific translatome of a rice thermo-sensitive genic male sterile line. Journal of Genetics and Genomics, 49(7), 624-635, 2022
    16) Shanjie Tang#, Chao Yang#, Dong Wang, Xian Deng, Xiaofeng Cao* and Xianwei Song*. Targeted DNA demethylation produces heritable epialleles in rice. Science China Life Sciences, 65 (4), 753-756, 2022
    17) Zhihong Liu#, Shanjie Tang#, Wentao Hu, Ruo Lv, Hailiang Mei, Rongxin Yang, Xianwei Song, Xiaofeng Cao*, and Dong Wang*. Precise editing of methylated cytosine in Arabidopsis thaliana using a human APOBEC3Bctd-Cas9 fusion. Science China Life Sciences, 65 (1), 219-222, 2022
    18) 宋显伟, 唐善杰, 曹晓风. 表观遗传调控与作物育种. 中国农业科技导报, 24 (12), 33-38, 2022
    19) Zhiyao Lv#, Rui Dai#, Haoran Xu#, Yongxin Liu, Bo Bai, Ying Meng, Haiyan Li, Xiaofeng Cao*, Yang Bai*, Xianwei Song*, Jingying Zhang*. The rice histone methylation regulates hub species of the root microbiota. Journal of Genetics and Genomics, (9), 836-843, 2021
    20)宋显伟,张保才,白 洋,潘多峰,邓向东,王竑晟,孙 波,曹晓风. 生物技术助力黑土地保护性利用的应用与思考.中国科学院院刊,36(12),1488-1496,2021
    21)曹晓风#*,孙 波#,陈化榜,周俭民,宋显伟,刘小京,邓向东,李秀军,赵玉国,张佳宝*,李家洋*. 我国边际土地产能扩增和生态效益提升的途径与研究进展. 中国科学院院刊,36(3),336-348,2021
    22) Fuyan Si#, Xiaofeng Cao, Xianwei Song* and Xian Deng*. Processing of coding and non-coding RNAs in plant development and environmental responses. Essays in Biochemistry, 64, 931-945, 2020
    23) Shukun Jiang#*, Chao Yang#, Quan Xu, Lizhi Wang, Xianli Yang, Xianwei Song, Jiayu Wang, Xijuan Zhang, Bo Li, Hongyu Li, Zhugang Li*, Wenhua Li*. Genetic Dissection of Germinability under Low Temperature by Building a Resequencing Linkage Map in japonica Rice. International Journal of Molecular Sciences, 21, 1284, 2020
    24) Xianwei Song#, Yan Li#, Xiaofeng Cao* and Yijun Qi*. MicroRNAs and Their Regulatory Roles in Plant–Environment Interactions. Annual Review of Plant Biology, 70: 489-525, 2019
    25) Rongxin Yang, Pingchuan Li, Hailiang Mei, Dong Wang, Jing Sun, Chao Yang, Lili Hao, Shouyun Cao, Chengcai Chu, Songnian Hu, Xianwei Song*, Xiaofeng Cao*. Fine-Tuning of MiR528 Accumulation Modulates Flowering Time in Rice. Molecular Plant, 12:1103-1113, 2019 (Cover story)
    26) Runlai Hang, Zhen Wang, Xian Deng, Chunyan Liu, Bin Yan, Chao Yang, Xianwei Song, Beixin Mo, and Xiaofeng Cao*. Ribosomal RNA Biogenesis and Its Response to Chilling Stress in Oryza sativa. Plant Physiology, 177:381-397, 2018
    27) Xianwei Song and Xiaofeng Cao*. Context and Complexity: Analyzing Methylation in Trinucleotide Sequences. Trends in Plant Science, 22 (5): 351-353, 2017
    28) Xianwei Song and Xiaofeng Cao*. Transposon-mediated epigenetic regulation contributes to phenotypic diversity and environmental adaptation in rice. Current Opinions in Plant Biology, 36:111-118, 2017
    29) Xiangjin Wei#, Xianwei Song#, Liya Wei#, Shaoqing Tang, Jing Sun, Peisong Hu, and Xiaofeng Cao*. An Epiallele of Rice AK1 Affects Photosynthetic Capacity. Journal of Integrative Plant Biology, 3: 158-163, 2017
    30) Jianguo Wu#, Rongxin Yang#, Zhirui Yang#, Shengze Yao, Shanshan Zhao, Yu Wang, Pingchuan Li, Xianwei Song, Lian Jin, Tong Zhou, Ying Lan, Lianhui Xie, Xueping Zhou, Chengcai Chu, Yijun Qi, Xiaofeng Cao* & Yi Li*. ROS Accumulation and Antiviral Defence Control by microRNA528 in Rice. Nature Plants, 3: 16203, 2017
    31) Xianwei Song and Xiaofeng Cao*. Small RNA Extraction and Detection in Rice (Oryza sativa). Current Protocols in Plant Biology, 1: 79-87, 2016
    32) Xian Deng, Xianwei Song, Liya Wei, Chunyan Liu and Xiaofeng Cao. Epigenetic Regulation and Epigenomic Landscape in rice. National Science Review, 3: 309–327, 2016
    33) Dayong Li, Zhiyuan Huang, Shuhui Song, Yeyun Xin, Donghai Mao, Qiming Lv, Ming Zhou, Dongmei Tian, Mingfeng Tian, Qi Wu, Xue Liu, Tingting Chen, Xianwei Song, Xiqin Fu, Bingran Zhao, Chengzhi Liang, Aihong Li, Guozhen, Liu, Shigui Li, Songnian Hu, Xiaofeng Cao, Jun Yu, Longping Yuan, Caiyan Chen and Lihuang Zhu. Integrated analysis of phenome, genome, and transcriptome of hybrid rice uncovered multiple heterosis-related loci for yield increase. Proceedings of the National Academy of Sciences of the United States of America, 113(41): E6026-E6035. 2016
    34) Xiangqian Zhang#, Jing Sun#, Xiaofeng Cao and Xianwei Song*. Epigenetic Mutation of RAV6 Affects Leaf Angle and Seed Size in Rice. Plant Physiology, 169:2118-2128, 2015
    35) Liya Wei#, Lianfeng Gu#, Xianwei Song#, Xiekui Cui, Zhike Lu, Ming Zhou, Lulu Wang, Fengyi Hu, Jixian Zhai, Blake C. Meyers and Xiaofeng Cao*. Dicer-like 3 produces transposable element-associated 24-nt siRNAs that control agricultural traits in rice. Proceedings of the National Academy of Sciences of the United States of America, 111, 3877-3882, 2014
    36) Hai Zhou#, Ming Zhou#, Yuanzhu Yang, Jing Li, Liya Zhu, Dagang Jiang, Jingfang, Dong, Qinjian Liu, Lianfeng Gu, Lingyan Zhou, Mingji Feng, Peng Qin, Xiaochun Hu, Chengli Song, Jinfeng Shi, Xianwei Song, Erdong Ni, Xiaojin Wu, Qiyun Deng, Zhenlan Liu, Mingsheng Chen, Yao-Guang Liu, Xiaofeng Cao*&Chuxiong Zhuang*. RNaseZS1processesUbL40mRNAs and controls thermo-sensitive genic male sterility in rice. Nature Communications. 5: 4884, 2014
    37) Xianwei Song#, Xiuying Liu#, Xiaofeng Cao* and Xiu-jie Wang*. Non-coding regulatory RNAs. GENETICS AND GENOMICS OF RICE, Edited by Drs. Qifa Zhang and Rod Wing, 2013
    38) Lulu Wang, Xianwei Song, Liangfeng Gu, Xin Li, Shouyun Cao, Chengcai Chu, Xia Cui, Xuemei Chen and Xiaofeng Cao*. NOT2 Proteins Promote Pol II-dependent Transcription and Interact with Multiple miRNA Biogenesis Factors in Arabidopsis. The Plant Cell, 25: 715-727, 2013
    39) Xiekui Cui#, Ping Jin#, Xia Cui, Lianfeng Gu, Zhike Lu, Yongming Xue, Liya Wei, Jianfei Qi, Xianwei Song, Ming Luo, Gynheung An and Xiaofeng Cao*. Control of Transposon Activity by a Histone H3K4 Demethylase in Rice. Proceedings of the National Academy of Sciences of the United States of America, 110: 1953–1958, 2013
    40) Xianwei Song#, Dekai Wang#, Lijia Ma, Zhiyu Chen, Pingchuan Li, Xia Cui, Chunyan Liu, Shouyun Cao, Chengcai Chu, Yuezhi Tao and Xiaofeng Cao*. Rice RNA-dependent RNA Polymerase 6 Acts in Small RNA Biogenesis and Spikelet Development. The Plant Journal, 71:378-389, 2012
    41) Xianwei Song#, Pingchuan Li#, Jixian Zhai#, Ming Zhou#, Lijia Ma, Bin Liu, Dong-Hoon Jeong, Mayumi Nakano, Shouyun Cao, Chunyan Liu, Chengcai Chu, Xiu-Jie Wang, Pamela J. Green, Blake C. Meyers and Xiaofeng Cao*. Roles of DCL4 and DCL3b in Rice Phased Small RNA Biogenesis. The Plant Journal, 69:462-474, 2012
    42) Ming Zhou#, Lianfeng Gu#, Pingchuan Li, Xianwei Song, Liya Wei, Zhiyu Chen, and Xiaofeng Cao*. Degradome Sequencing Reveals Endogenous Small RNA Targets in Rice (Oryza sativa L. ssp. indica). Frontier in Biology, 5: 67-90, 2010
    43) Bin Liu, Zhiyu Chen, Xianwei Song, Chunyan Liu, Xia Cui, Xianfeng Zhao, Jun Fang, Wenying Xu, Huiyong Zhang, Xiujie Wang, Chengcai Chu, Xingwang Deng, Yongbiao Xue and Xiaofeng Cao*. Oryza sativa Dicer-like4 Reveals a Key Role for Small Interfering RNA Silencing in Plant Development. The Plant Cell, 19: 2705-2718, 2007