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    姓　　名： 韩方普
    职　　称： 研究员
    职　　务：
    电话/传真： 86-10-64807926
    电子邮件： fphan@genetics.ac.cn
    实验室主页：
    研究方向： 植物染色体生物学

    简历介绍：

    韩方普，博士，研究员，博士生导师

     

            东北师范大学遗传与细胞研究所获博士学位；1998-2001年在以色列 Weizmann 研究所做博士后，从事小麦多倍体基因组进化研究；2001-2004年在加拿大农业部做Visiting Fellow 和 Biologist，从事小麦抗赤霉病分子标记和种质创新及小麦多倍体基因组进化研究；2004-2008年在美国 University of Missouri-Columbia 从事玉米功能基因组及植物人工染色体研究。韩方普研究组主要从事小麦和玉米功能基因组、小麦染色体工程育种及植物人工染色体研究。

    研究领域：

    主要研究领域
     

    远缘杂交育种和多倍体基因组进化

             重点研究多倍体作物小麦及小偃麦的形成过程及机制。高效地转移、鉴定和跟踪外缘基因，发掘具有重要育种价值的易位系和关键基因。揭示多倍体作物中基因组之间的互作与优势的分子机理；创制、鉴定和评价小片段易位系和近缘种全基因组渗入系；分离并详细研究来自野生物种的高产、优质、抗病虫和抗逆基因；培育高产稳产、优质高效、抗病和耐逆的作物新品种。

     

    植物着丝粒的结构和功能

             在玉米着丝粒功能研究领域：研究玉米染色体着丝粒功能“失活-激活”的表观遗传学调控机制。探讨DNA甲基化、组蛋白修饰以及小RNA与着丝粒功能的内在联系。

     

    植物减数分裂

             减数分裂过程中同源染色体的配对起始、重组、取向和分离的分子机理是国际上研究的热点。将以小麦和玉米的特殊突变体为材料来研究上述问题，分离减数分裂相关基因并阐明其功能。

     

    植物人工染色体

             将利用不同的方法构建植物人工染色体。构建和优化适合多基因或完整代谢途径遗传转化的转基因载体。

     

    植物基因定点突变及定向重组

             随着玉米基因组序列的完成，需要发展一种有效的方法来利用已知的序列信息进行定点突变和置换，避免位置效应而进行重要基因功能的鉴定。利用人工锌指蛋白核酸酶技术对小麦和玉米的基因进行定点突变和置换， 将对基因功能研究和分子设计育种提供新的方法。

    社会任职：

    获奖及荣誉：

    承担科研项目情况：

    代表论著：

    发表论文：
     
    2026
    1. Liu Y, He W, Wang C, Yi C, Guo T, Zhu C, Liu Q, Han F. (2026) Two near-complete assemblies reveal R-subgenome structural and centromeric divergence associated with reproductive isolation in hexaploid triticale. iMeta DOI: 10.1002/imt2.70155.
    2. Zhang K, Shen L, Sun Y, Liu C, Yi C, Liu Y, Liu Z, Han F, & Liu Q. (2026) Sequence-directed R-loop formation coupled with DNA methylation reprogramming during polyploidization of Brachypodium. Plant J 126(5):e70957.
    3. Wang C, Fu S, Yi C, Chang Y, Wang M, Zhou C, Wang Z, Fan R, Yuan J, Wang T, Wang Y, Yang W, Liu Y, & Ye X, & Han F. (2026) An NLR-transposase fusion gene from rye provides broadly effective resistance to stripe rust in wheat. Nat Plants 12(4):818–829.
    4. Hu J, Cheng J, Li Y, Han F, Zhang L, Wu Y. (2026) The pyramiding of QYr.cib-3AS and YrT14 enhances wheat resistance to stripe rust. Front Plant Sci 17:1802598.
    5. Zhu C, Liu Q, Yi C, Liu C, Zhang K, He W, Zhou C, Guo T, Han F, & Liu Y. (2026) Integrated genomic and epigenetic architecture of de novo centromere formation in barley. Plant J 125(1):e70651.
    2025
    6. Zhou J, Huang Y, Ma H, Chen Y, Chen C, Han F, & Su H. (2025) Adaptation of centromeres to breakage through local genomic and epigenomic remodeling in wheat. Genome Res 35(11):2461–2471.
    7. Wang C, Chang Y, Wang M, Wang J, Liu C, Fan C, Yi C, Zhou C, Yuan J, Yang W, Liu D, Wang T, Liu Y, Ye X, & Han F. (2025) The Yr9 gene encoding a CC-NBS-LRR protein in the 1RS-1BL translocation confers wheat stripe rust resistance. Sci China Life Sci 68(9):2804–2806.
    8. Shen L, Yi C, Liu Y, Han F, & Feng J. (2025) Two complete telomere-to-telomere genome assemblies of Medicago reveal the landscape and evolution of its centromeres. Mol Plant 18(9):1409–1412.
    9. Huang Y, Liu Y, Liu C, Yi C, Lai J, Ling H, Su H, & Han F. (2025) Distinct evolutionary trajectories of subgenomic centromeres in polyploid wheat. Genome Biol 26(1):271.
    10. Yi C, Liu Q, Zhu C, Liu C, Zhou C, He W, Wang C, Yuan J, Liu Y, & Han F. (2025) High-resolution genome assembly reveals retrotransposon-mediated centromere dynamics in rye. Genome Biol 26(1):308.
    11. Liu Y, Liu Q, Yi C, Liu C, Shi Q, Wang M, Han F. (2025) Past innovations and future possibilities in plant chromosome engineering. Plant Biotechnol J 23(3):695–708.
    12. Liu Q, Liu Y, Yi C, Gao Z, Zhang Z, Zhu C, Birchler JA, & Han F. (2025) Genome assembly of the maize B chromosome provides insight into its epigenetic characteristics and effects on the host genome. Genome Biol 26(1):47.
    2024
    13. Tang Z, Liu Q, Pan Z, Liu C, Dong J, Han F, & Fu S. (2024) Stable minichromosome and functional neocentromere derived from rye 7R chromosome arm. BMC Plant Biol 24(1):1185.
    14. Ye X, & Han F. (2024) Editorial: Applications of fast breeding technologies in crop improvement and functional genomics study. Front Plant Sci 15:1460642.
    15. Huang Y, Shi Q, Zhou C, Wang C, Liu Y, Yi C, Su H, & Han F. (2024) Wide hybridizations reveal the robustness of functional centromeres in Triticum–Aegilops species complex lines. J Genet Genomics 51(5):570–573.
    16. Miao L, Xu W, Liu Y, Huang X, Chen Z, Wang H, Wang Z, Chen Y, Song Q, Zhang J, Han F, Peng H, Yao Y, Xin M, Hu Z, Ni Z, Sun Q, Xing J, Guo W. (2024) Reshaped DNA methylation cooperating with homoeolog-divergent expression promotes improved root traits in synthesized tetraploid wheat. New Phytol 242(2):507–523.
    17. Chen C, Wu S, Sun Y, Zhou J, Chen Y, Zhang J, Birchler JA, Han F, Yang N, Su H. (2024) Three near-complete genome assemblies reveal substantial centromere dynamics from diploid to tetraploid in Brachypodium genus. Genome Biol 25(1):63.
    18. Liu C, Huang Y, Guo X, Yi C, Liu Q, Zhang K, Zhu C, Liu Y, & Han F. (2024) Young retrotransposons and non-B DNA structures promote the establishment of dominant rye centromere in the 1RS.1BL fused centromere. New Phytol 241(2):607–622.
    19. Liu C, Fu S, Yi C, Liu Y, Huang Y, Guo X, Zhang K, Liu Q, Birchler JA, & Han F. (2024) Unveiling the distinctive traits of functional rye centromeres: Minisatellites, retrotransposons, and R-loop formation. Sci China Life Sci 67:1989–2002.
    20. Yi C, Liu Q, Huang Y, Liu C, Guo X, Fan C, Zhang K, Liu Y, & Han F. (2024) Non-B-form DNA is associated with centromere stability in newly-formed polyploid wheat. Sci China Life Sci 67(7):1479–1488.
    21. Zhang J, Fan C, Liu Y, Shi Q, Sun Y, Huang Y, Yuan J, & Han F. (2024) Cytological analysis of the diploid-like inheritance of newly synthesized allotetraploid wheat. Chromosome Res 32(1):1.
    22. Qiu Y, Han Z, Liu N, Yu M, Zhang S, Chen H, Tang H, Zhao Z, Wang K, Lin Z, Han F, & Ye X. (2024) Effects of Aegilops longissima chromosome 1Sl on wheat bread-making quality in two types of translocation lines. Theor Appl Genet 137(1):2.
    2023
    23. Liu Y, Yi C, Fan C, Liu Q, Liu S, Shen L, Zhang K, Huang Y, Liu C, Wang Y, Tian Z, & Han F. (2023) Pan-centromere reveals widespread centromere repositioning of soybean genomes. Proc Natl Acad Sci U S A 120(42):e2310177120.
    24. Liu Q, Yi C, Zhang Z, Su H, Liu C, Huang Y, Li W, Hu X, Liu C, Birchler JA, Liu Y, Han F. (2023) Non-B-form DNA tends to form in centromeric regions and has undergone changes in polyploid oat subgenomes. Proc Natl Acad Sci U S A 120(1):e2211683120.
    25. Guo X, Shi Q, Wang M, Yuan J, Zhang J, Wang J, Liu Y, Su H, Wang Z, Li J, Liu C, Ye X, Han F. (2023) Functional analysis of the glutathione S-transferases from Thinopyrum and its derivatives on wheat Fusarium head blight resistance. Plant Biotechnol J 21(6):1091–1093.
    26. Guo X, Shi Q, Liu Y, Su H, Zhang J, Wang M, Wang C, Wang J, Zhang K, Fu S, Hu X, Jing D, Wang Z, Li J, Zhang P, Liu C, Han F. (2023) Systemic development of wheat–Thinopyrum elongatum translocation lines and their deployment in wheat breeding for Fusarium head blight resistance. Plant J 114(6):1475–1489.
    27. Huang Y, Liu Y, Guo X, Fan C, Yi C, Shi Q, Su H, Liu C, Yuan J, Liu D, Yang W, Han F. (2023) New insights on the evolution of nucleolar dominance in newly resynthesized hexaploid wheat Triticum zhukovskyi. Plant J 115(5):1298–1315.
    28. Shi Q, Guo X, Su H, Zhang Y, Hu Z, Zhang J, Han F. (2023) Autoploid origin and rapid diploidization of the tetraploid Thinopyrum elongatum revealed by genome differentiation and chromosome pairing in meiosis. Plant J 113(3):536–545.
    29. Guo X, Huang Y, Wang J, Fu S, Wang C, Wang M, Zhou C, Hu X, Wang T, Yang W, Han F. (2023) Development and cytological characterization of wheat–Thinopyrum intermedium translocation lines with novel stripe rust resistance gene. Front Plant Sci 14:1135321.
    2022
    30. Guo X, Wang M, Kang H, Zhou Y, Han F. (2022) Distribution, polymorphism and function characteristics of the GST-encoding Fhb7 in Triticeae. Plants (Basel) 11(16):2074.
    31. Liu C, Wang J, Fu S, Wang L, Li H, Wang M, Huang Y, Shi Q, Zhou Y, Guo X, Zhu C, Zhang J, Han F. (2022) Establishment of a set of wheat–rye addition lines with resistance to stem rust. Theor Appl Genet 135(7):2469–2480.
    32. Huang Y, Liu Y, Liu C, Birchler JA, Han F. (2022) Prospects and challenges of epigenomics in crop improvement. Genes Genomics 44(3):251–257.
    33. Zhou J, Liu Y, Guo X, Birchler JA, Han F, Su H. (2022) Centromeres: From chromosome biology to biotechnology applications and synthetic genomes in plants. Plant Biotechnol J 20(11):2051–2063.
    34. Konkin D, Hsueh YC, Kirzinger M, Kubaláková M, Haldar A, Balcerzak M, Han F, Fedak G, Doležel J, Sharpe A, Ouellet T. (2022) Genomic sequencing of Thinopyrum elongatum chromosome arm 7EL, carrying Fusarium head blight resistance, and characterization of its impact on the transcriptome of the introgressed line CS-7EL. BMC Genomics 23(1):228.
    2021
    35. Su H, Liu Y, Wang C, Liu Y, Feng C, Sun Y, Yuan J, Birchler JA, Han F. (2021) Knl1 participates in spindle assembly checkpoint signaling in maize. Proc Natl Acad Sci U S A 118(20):e2022357118.
    36. Blavet N, Yang H, Su H, Solanský P, Douglas RN, Karafiátová M, Šimková L, Zhang J, Liu Y, Hou J, Shi X, Chen C, El-Walid M, McCaw ME, Albert PS, Gao Z, Zhao C, Ben-Zvi G, Glick L, Kol G, Shi J, Vrána J, Šimková H, Lamb JC, Newton K, Dawe RK, Doležel J, Ji T, Baruch K, Cheng J, Han F, Birchler JA, Bartoš J. (2021) Sequence of the supernumerary B chromosome of maize provides insight into its drive mechanism and evolution. Proc Natl Acad Sci U S A 118(23):e2104254118.
    37. Liu Y, Wang C, Su H, Birchler JA, Han F. (2021) Phosphorylation of histone H3 by Haspin regulates chromosome alignment and segregation during mitosis in maize. J Exp Bot 72(4):1046–1058.
    38. Liu Q, Liu Y, Shi Q, Su H, Wang C, Birchler JA, Han F. (2021) Emerging roles of centromeric RNAs in centromere formation and function. Genes Genomics 43(3):217–226.
    39. Liu Y, Liu Q, Su H, Liu K, Xiao X, Li W, Sun Q, Birchler JA, Han F. (2021) Genome-wide mapping reveals R-loops associated with centromeric repeats in maize. Genome Res 31(8):1409–1418.
    40. Zhang Y, Fan C, Chen Y, Wang R, Zhang X, Han F, Hu Z. (2021) Genome evolution during bread wheat formation unveiled by the distribution dynamics of SSR sequences on chromosomes using FISH. BMC Genomics 22(1):55.
    41. Haldar A, Tekieh F, Balcerzak M, Wolfe D, Lim D, Joustra K, Konkin D, Han F, Fedak G, Ouellet T. (2021) Introgression of Thinopyrum elongatum DNA fragments carrying resistance to Fusarium head blight into Triticum aestivum cultivar Chinese Spring is associated with alteration of gene expression. Genome 64(11):1009–1020.
    42. Fedak G, Chi D, Wolfe D, Ouellet T, Cao W, Han F, Xue A. (2021) Transfer of Fusarium head blight resistance from Thinopyrum elongatum to bread wheat cultivar Chinese Spring. Genome 64(11):997–1008.
    43. Douglas RN, Yang H, Zhang B, Chen C, Han F, Cheng J, Birchler JA. (2021) De novo centromere formation on chromosome fragments with an inactive centromere in maize (Zea mays). Chromosome Res 29(3–4):313–325.
    2020
    44. Liu Y, Su H, Zhang J, Shi L, Liu Y, Zhang B, Bai H, Liang S, Gao Z, Birchler JA, Han F. (2020) Rapid birth or death of centromeres on fragmented chromosomes in maize. Plant Cell 32(10):3113–3123.
    45. Zhang J, Feng C, Su H, Liu Y, Liu Y, Han F. (2020) The cohesin complex subunit ZmSMC3 participates in meiotic centromere pairing in maize. Plant Cell 32(4):1323–1336.
    46. Liu Y, Su H, Zhang J, Liu Y, Feng C, Han F. (2020) Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize. PLoS Biol 18(1):e3000582.
    47. Wang H, Liu Y, Yuan J, Zhang J, Han F. (2020) The condensin subunits SMC2 and SMC4 interact for correct condensation and segregation of mitotic maize chromosomes. Plant J 102(3):467–479.
    48. Feng C, Yuan J, Bai H, Liu Y, Su H, Liu Y, Shi L, Gao Z, Birchler JA, Han F. (2020) The deposition of CENH3 in maize is stringently regulated. Plant J 102(1):6–17.
    2019
    49. Wang J, Shi Q, Guo X, Han F. (2019) Establishment and characterization of a complete set of Triticum durum–Thinopyrum elongatum monosomic addition lines with resistance to Fusarium head blight in wheat. J Genet Genomics 46(11):547–549.
    50. Su H, Liu Y, Liu C, Shi Q, Huang Y, Han F. (2019) Centromere satellite repeats have undergone rapid changes in polyploid wheat subgenomes. Plant Cell 31(9):2035–2051.
    2018
    51. Su H, Liu Y, Liu Y, Birchler JA, Han F. (2018) The behavior of the maize B chromosome and centromere. Genes (Basel) 9(10):476.
    52. Han F, Lamb JC, McCaw ME, Gao Z, Zhang B, Swyers NC, Birchler JA. (2018) Meiotic studies on combinations of chromosomes with different sized centromeres in maize. Front Plant Sci 9:785.
    53. Feng C, Su H, Bai H, Wang R, Liu Y, Guo X, Liu C, Zhang J, Yuan J, Birchler JA, Han F. (2018) High-efficiency genome editing using a dmc1 promoter-controlled CRISPR/Cas9 system in maize. Plant Biotechnol J 16(11):1848–1857.
    54. Birchler JA, Han F. (2018) Barbara McClintock’s unsolved chromosomal mysteries: Parallels to common rearrangements and karyotype evolution. Plant Cell 30(4):771–779.
    2017
    55. Yuan J, Shi Q, Guo X, Liu Y, Su H, Guo X, Lv Z, Han F. (2017) Site-specific transfer of chromosomal segments and genes in wheat engineered chromosomes. J Genet Genomics 44(11):531–539.
    56. Liu Y, Su H, Liu Y, Zhang J, Dong Q, Birchler JA, Han F. (2017) Cohesion and centromere activity are required for phosphorylation of histone H3 in maize. Plant J 92(6):1121–1131.
    57. Zhang J, Han F. (2017) Centromere pairing precedes meiotic chromosome pairing in plants. Sci China Life Sci 60(11):1197–1202.
    58. Wang J, Liu Y, Su H, Guo X, Han F. (2017) Centromere structure and function analysis in wheat–rye translocation lines. Plant J 91(2):199–207.
    59. Su H, Liu Y, Dong Q, Feng C, Zhang J, Liu Y, Birchler JA, Han F. (2017) Dynamic location changes of Bub1-phosphorylated H2AThr133 with CENH3 nucleosome in maize centromeric regions. New Phytol 214(2):682–694.
    2016
    60. Su H, Liu Y, Liu Y, Lv Z, Xie S, Gao Z, Pang J, Wang X, Han F. (2016) Dynamic chromatin changes associated with de novo centromere formation in maize euchromatin. Plant J 88(5):854–866.
    61. Guo X, Su H, Shi Q, Fu S, Wang J, Zhang X, Han F. (2016) De novo centromere formation and centromeric sequence expansion in wheat and its wide hybrids. PLoS Genet 12(4):e1005997.
    62. Feng C, Yuan J, Wang R, Liu Y, Birchler JA, Han F. (2016) Efficient targeted genome modification in maize using CRISPR/Cas9 system. J Genet Genomics 43(1):37–43.
    2015
    63. Liu Y, Su H, Pang J, Gao Z, Wang X, Birchler JA, Han F. (2015) Sequential de novo centromere formation and inactivation on a chromosomal fragment in maize. Proc Natl Acad Sci U S A 112(11):E1263–E1271.
    64. Feng C, Liu Y, Su H, Wang H, Birchler JA, Han F. (2015) Recent advances in plant centromere biology. Sci China Life Sci 58(3):240–245.
    65. Guo X, Shi Q, Wang J, Hou Y, Wang Y, Han F. (2015) Characterization and genome changes of new amphiploids from wheat wide hybridization. J Genet Genomics 42(8):459–461.
    66. Yuan J, Guo X, Hu J, Lv Z, Han F. (2015) Characterization of two CENH3 genes and their roles in wheat evolution. New Phytol 206(2):839–851.
    2014
    67. Guo X, Han F. (2014) Asymmetric epigenetic modification and elimination of rDNA sequences by polyploidization in wheat. Plant Cell 26(11):4311–4327.
    68. Zhang J, Zhang B, Su H, Birchler JA, Han F. (2014) Molecular mechanisms of homologous chromosome pairing and segregation in plants. J Genet Genomics 41(3):117–123.
    69. Zhang B, Dong Q, Su H, Birchler JA, Han F. (2014) Histone phosphorylation: Its role during cell cycle and centromere identity in plants. Cytogenet Genome Res 143(1–3):144–149.
    2013
    70. Zhang J, Pawlowski WP, Han F. (2013) Centromere pairing in early meiotic prophase requires active centromeres and precedes installation of the synaptonemal complex in maize. Plant Cell 25(10):3900–3909.
    71. Fu S, Lv Z, Gao Z, Wu H, Pang J, Zhang B, Dong Q, Guo X, Wang X, Birchler JA, Han F. (2013) De novo centromere formation on a chromosome fragment in maize. Proc Natl Acad Sci U S A 110(15):6033–6036.
    72. Zhang B, Lv Z, Pang J, Liu Y, Guo X, Fu S, Li J, Dong Q, Wu H, Gao Z, Wang X, Han F. (2013) A functional centromere after loss of centromeric and gain of ectopic sequences. Plant Cell 25(6):1979–1989.
    73. Zhang H, Bian Y, Gou X, Zhu B, Xu C, Qi B, Li N, Rustgi S, Zhou H, Han F, Jiang J, von Wettstein D, Liu B. (2013) Persistent whole-chromosome aneuploidy is generally associated with nascent allohexaploid wheat. Proc Natl Acad Sci U S A 110(9):3447–3452.
    74. Fu S, Lv Z, Guo X, Zhang X, Han F. (2013) Alteration of terminal heterochromatin and chromosome rearrangements in derivatives of wheat–rye hybrids. J Genet Genomics 40(8):413–420.
    75. Birchler JA, Han F. (2013) Centromere epigenetics in plants. J Genet Genomics 40(5):201–204.
    76. Gao Z, Han F, Danilova TV, Lamb JC, Albert PS, Birchler JA. (2013) Labeling meiotic chromosomes in maize with fluorescence in situ hybridization. Methods Mol Biol 990:35–43.
    77. Masonbrink R, Fu S, Han F, Birchler JA. (2013) Heritable loss of replication control of a minichromosome derived from the B chromosome of maize. Genetics 193(1):77–84.
    2012
    78. Dong Q, Han F. (2012) Phosphorylation of histone H2A is associated with centromere function and maintenance in meiosis. Plant J 71(5):800–809.
    79. Fu S, Lv Z, Qi B, Guo X, Li J, Liu B, Han F. (2012) Molecular cytogenetic characterization of wheat–Thinopyrum elongatum addition, substitution and translocation lines with a novel source of resistance to wheat Fusarium head blight. J Genet Genomics 39(2):103–110.
    80. Fu S, Gao Z, Birchler JA, Han F. (2012) Dicentric chromosome formation and epigenetics of centromere formation in plants. J Genet Genomics 39(3):125–130.
    2011
    81. Gao Z, Fu S, Dong Q, Han F, Birchler JA. (2011) Inactivation of a centromere during the formation of a translocation in maize. Chromosome Res 19(6):755–761.
    82. Koo DH, Han F, Birchler JA, Jiang J. (2011) Distinct DNA methylation patterns associated with active and inactive centromeres of the maize B chromosome. Genome Res 21(6):908–914.
    83. Birchler JA, Gao Z, Sharma A, Presting GG, Han F. (2011) Epigenetic aspects of centromere function in plants. Curr Opin Plant Biol 14(2):217–222.
    84. Yin W, Birchler JA, Han F. (2011) Maize centromeres: Where sequence meets epigenetics. Front Biol 6:102–108.
    85. Zhao N, Xu L, Li M, Zhang H, Zhu B, Qi B, Xu C, Han F, Liu B. (2011) Chromosomal and genome-wide molecular changes associated with initial stages of allohexaploidization in wheat can be transit and incidental. Genome 54(8):692–699.
    86. Zhao N, Zhu B, Li M, Wang L, Xu L, Zhang H, Zheng S, Qi B, Han F, Liu B. (2011) Extensive and heritable epigenetic remodeling and genetic stability accompany allohexaploidization of wheat. Genetics 188(3):499–510.
    2009
    87. Han F, Gao Z, Birchler JA. (2009) Reactivation of an inactive centromere reveals epigenetic and structural components for centromere specification in maize. Plant Cell 21(7):1929–1939.
    88. Birchler JA, Han F. (2009) Maize centromeres: Structure, function, epigenetics. Annu Rev Genet 43:287–303.
    89. Birchler JA, Gao Z, Han F. (2009) Pairing in plants: Import is important. Proc Natl Acad Sci U S A 106(47):19751–19752.
    90. Wolfgruber TK, Sharma A, Schneider KL, Albert PS, Koo DH, Shi J, Gao Z, Han F, Lee HR, Xu R, Allison J, Birchler JA, Jiang J, Dawe RK, Presting GG. (2009) Maize centromere structure and evolution: Sequence analysis of centromeres 2 and 5 reveals a major role for retrotransposons. PLoS Genet 5(12):e1000743.
    2007
    91. Han F, Gao Z, Yu W, Birchler JA. (2007) Minichromosome analysis of chromosome pairing, disjunction, and sister chromatid cohesion in maize. Plant Cell 19(12):3853–3863.
    92. Han F, Lamb JC, Yu W, Gao Z, Birchler JA. (2007) Centromere function and nondisjunction are independent components of the maize B chromosome accumulation mechanism. Plant Cell 19(2):524–533.
    93. Yu W, Lamb JC, Han F, Birchler JA. (2007) Cytological visualization of DNA transposons and their transposition pattern in somatic cells of maize. Genetics 175(1):31–39.
    94. Yu W, Han F, Vega JM, Gao Z, Birchler JA. (2007) Construction and behavior of engineered minichromosomes in maize. Proc Natl Acad Sci U S A 104(21):8924–8929.
    2006
    95. Han F, Lamb JC, Birchler JA. (2006) High frequency of centromere inactivation resulting in stable dicentric chromosomes of maize. Proc Natl Acad Sci U S A 103(9):3238–3243.
     

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