PUBLICATIONS ( * Corresponding author; 1 co-first author)
PEER REVIEWED RESEARCH ARTICLES
2024
1. Liang R1, He Z1, Zhao KT1, Zhu H, Hu J, Liu G, Gao Q, Liu M, Zhang R, Qiu JL, Gao C*, Prime editing using CRISPR-Cas12a and circular RNAs in human cells. Nature Biotechnology, DOI: 10.1038/s41587-023-02095-x (2024).
2023
2．Hu J1, Sun Y1, Li B, Liu Z1, Wang Z, Gao Q, Guo M, Liu G, Zhao KT*, Gao C*，Strand-preferred base editing of organellar and nuclear genomes using CyDENT. Nature Biotechnology, DOI: 10.1038/s41587-023-01910-9 (2023)
3．Huang J1, Lin Q1, Fei H1, He Z1, Xu H, Li Y, Qu K, Han P, Gao Q, Li B, Liu G, Zhang L, Hu J, Zhang R, Zuo E, Luo Y, RanY, Qiu JL, Zhao KT*, Gao C*, Discovery of new deaminase functions by structure-based protein clustering. Cell, 186, 3182-3195(2023).
4．Xing S, Sun Y, Li B, Li H, Zhao KT, Chen K*, Gao C*, Anthocyanin-assisted Agrobacterium infiltration for the rapid evaluation of genome editing efficiencies across multiple plant species. National Science Open, 2, 20220052 (2023).
5．Sun C1, Lei Y1, Li B1, Gao Q, Li Y, Cao W, Yang C, Li H, Wang Z, Li Y, Wang Y, Liu J, Zhao KT, Gao C*, Precise integration of large DNA sequences in plant genomes using PrimeRoot editors. Nature Biotechnology, DOI: 10.1038/s41587-023-01769-w (2023).
6．Xue C, Qiu F, Wang Y, Li B, Zhao KT, Chen K,
Gao C*, Tuning plant phenotypes by precise, graded downregulation of gene expression.
Nature Biotechnology, 41, 1758–1764 (2023).
7．Jin S1, Lin Q1, Gao Q, Gao C*, Optimized prime editing in monocot plants using PlantPegDesigner and engineered plant prime editors (ePPEs). Nature Protocols, 18, 831-853 (2023).
2022
8．Xu F1, Tang J1, Wang S, Cheng X, Wang H, Ou S, Gao S, Li B, Qian Y, Gao C*, Chu C*, Antagonistic control of seed dormancy in rice by two bHLH transcription factors. Nature Genetics, 54, 1972-1982 (2022).
9．Tu T1, Song Z1, Liu X1, Wang S1, He X1, Xi H, Wang J, Yan T, Chen H, Zhang Z, Lv X, Lv J, Huang XF, Zhao J, Lin CP, Gao C*, Zhang J*, Gu F*, A precise and efficient adenine base editor. Molecular therapy, 30(9), 2933-2941 (2022).
10．Zong Y1, Liu Y1, Xue C1, Li B, Li X, Wang Y, Li J, Liu G, Huang X, Cao X*, Gao C*, An engineered prime editor with enhanced editing efficiency in plants. Nature Biotechnology, 40,1394-1402 (2022).
11．Li S1, Lin D1, Zhang Y1, Deng M1, Chen Y, Lv B, Li B, Lei Y, Wang Y, Zhao L, Liang Y, Liu J, Chen K, Liu Z, Xiao J*, Qiu JL*, Gao C*, Genome-edited powdery mildew resistance in wheat without growth penalties. Nature, 602, 455-460 (2022).
12．Luo J1, Rouse MN1, Hua L, Li H, Li B, Li T, Zhang W, Gao C, Wang Y*, Dubcovsky J*, Chen S*, Identification and characterization of Sr22b, a new allele of the wheat stem rust resistance gene Sr22 effective against the Ug99 race group. Plant Biotechnology Journal, 20, 554-563 (2022).
13．Wang N, Fan X, He M, Hu Z, Tang C, Zhang S, Lin D, Gan P, Wang J, Huang X, Gao C, Kang Z, Wang X*, Transcriptional repression of TaNOX10 by TaWRKY19 compromises ROS generation and enhances wheat susceptibility to stripe rust. Plant Cell, 34, 1784-1803 (2022).
14．Qiu F1, Xing S1, Xue C, Liu J, Chen K, Chai T*, Gao C*, Transient expression of a TaGRF4-TaGIF1 complex stimulates wheat regeneration and improves genome editing. Science China Life Sciences, 65, 731-738 (2022).
2021
15．Luo G1, Shen L1, Zhao S1, Li R1, Song Y, Song S, Yu K, Yang W, Li X, Sun J, Wang Y, Gao C, Liu D*, Zhang A*, Genome-wide identification of seed storage protein gene regulators in wheat through coexpression analysis. The Plant Journal, 108, 1704-1720 (2021).
16．Guo M1, Wang Q1, Zong Y1, Nian J, Li H, Li J, Wang T, Gao C*, Zuo J*, Genetic manipulations of TaARE1 boost nitrogen utilization and grain yield in wheat. Journal of Genetics and Genomics, 48, 950-953 (2021).
17．Li T1, Hu J1, Sun Y, Li B, Zhang D, Li W, Liu J, Li D, Gao C, Zhang Y*, Wang Y*, Highly efficient heritable genome editing in wheat using an RNA virus and bypassing tissue culture. Molecular Plant, 14, 1787-1798 (2021).
18．Xu S, Dong Q, Deng M, Lin D, Xiao J, Cheng P, Xing L, Niu Y, Gao C, Zhang W, Xu Y, Chong K*, The vernalization-induced long non-coding RNA VAS functions with the transcription factor TaRF2b to promote TaVRN1 expression for flowering in hexaploid wheat. Molecular Plant, 14, 1525-1538 (2021).
19．Lin Q1, Zhu Z1, Liu G1, Sun C, Lin D, Xue C, Li S, Zhang D, Gao C, Wang Y*, Qiu JL*, Genome editing in plants with MAD7 nuclease. Journal of Genetics and Genomics, 48, 444-451 (2021).
20．Jin S1, Lin Q1, Luo Y1, Zhu Z1, Liu G, Li Y, Chen K, Qiu JL, Gao C*, Genome-wide specificity of prime editors in plants. Nature Biotechnology, 39, 1292-1299 (2021).(SCI Citations: 46)
21．Lin Q1, Jin S1, Zong Y1, Yu H1, Zhu Z, Liu G, Kou L, Wang Y, Qiu JL, Li J*, Gao C*, High-efficiency prime editing with optimized, paired pegRNAs in plants. Nature Biotechnology, 39, 923-927 (2021).
22．Yu H1*, Lin T1, Meng X1, Du H1, Zhang J1, Liu G, Chen M, Jing Y, Kou L, Li X, Gao Q, Liang Y, Liu X, Fan Z, Liang Y, Cheng Z, Chen M, Tian Z, Wang Y, Chu C, Zuo J, Wan J, Qian Q, Han B, Zuccolo A, Wing RA, Gao C*, Liang C*, Li J*, A route to de novo domestication of wild allotetraploid rice. Cell, 184, 1156-1170 (2021).
23．Xu Y1, Lin Q1, Li X, Wang F, Chen Z, Wang J, Li W, Fan F, Tao Y, Jiang Y, Wei X, Zhang R, Zhu QH, Bu Q*, Yang J*, Gao C*, Fine-tuning the amylose content of rice by precise base editing of the Wx Gene. Plant Biotechnology Journal, 19, 11-13 (2021).
24．Jin S, Gao Q, Gao C*, An unbiased method for evaluating the genome-wide specificity of base editors in rice. Nature Protocols, 16, 431-457 (2021).
25．Luo G1, Shen L1, Song Y1, Yu K, Ji J, Zhang C, Yang W, Li X, Sun J, Zhan K, Cui D, Wang Y, Gao C, Liu D*, Zhang A*, The MYB family transcription factor TuODORANT1 from Triticum urartu and the homolog TaODORANT1 from Triticum aestivum inhibit seed storage protein synthesis in wheat. Plant Biotechnology Journal, 19, 1863-1877 (2021).
26．Zhang R1, Chen S1, Meng X1, Chai Z, Wang D, Yuan Y, Chen K, Jiang L*, Li J*, Gao C*, Generating broad-spectrum tolerance to ALS-inhibiting herbicides in rice by base editing. Science China Life Sciences, 64, 1624-1633 (2021).
2020
27．Jiang Y1, Chai Y1, Lu M1, Han X, Lin Q, Zhang Y, Zhang Q, Zhou Y, Wang X, Gao C*, Chen QJ*, Prime editing efficiently generates W542L and S621I double mutations in two ALS genes in maize. Genome Biology, 21, 257 (2020).
28．Xing S1, Chen K1, Zhu H, Zhang R, Zhang H, Li B, Gao C*, Fine-tuning sugar content in strawberry. Genome Biology, 21, 230 (2020).
29．Jin S1, Fei H1, Zhu Z1, Luo Y1, Liu J, Gao S, Zhang F, Chen YH, Wang Y*, Gao C*, Rationally designed APOBEC3B cytosine base editors with improved specificity. Molecular Cell, 79, 728-740 (2020).
30．Xie H1, Ge X1, Yang F, Wang B, Li S, Duan J, Lv X, Cheng C, Song Z, Liu C, Zhao J, Zhang Y, Wu J, Gao C, Zhang J*, Gu F*, High-fidelity SaCas9 identified by directional screening in human cells. PloS Biology, 18, e3000747 (2020).
31．Wang S1, Zong Y1, Lin Q1, Zhang H1, Chai Z, Zhang D, Chen K, Qiu JL, Gao C*, Precise, predictable multi-nucleotide deletions in rice and wheat using APOBEC-Cas9. Nature Biotechnology, 38, 1460-1465 (2020).
32．Fan R1, Chai Z1, Xing S, Chen K, Qiu F, Chai T, Qiu JL, Zhang Z*, Zhang H*, Gao C*, Shortening the sgRNA-DNA interface enables SpCas9 and eSpCas9(1.1) to nick the target DNA strand. Science China Life Sciences, 63, 1619-1630 (2020).
33．Li C, Zong Y, Jin S, Zhu H, Lin D, Li S, Qiu JL, Wang Y*, Gao C*, SWISS: multiplexed orthogonal genome editing in plants with a Cas9 nickase and engineered CRISPR RNA scaffolds. Genome Biology, 21, 141 (2020).
34．Wang H1, Sun S1, Ge W1, Zhao L1, Hou B, Wang K, Lyu Z, Chen L, Xu S, Guo J, Li M, Su P, Li X, Wang G, Bo C, Fang X, Zhuang W, Cheng X, Wu J, Dong L, Chen W, Li W, Xiao G, Zhao J, Hao Y, Xu Y, Gao Y, Liu W, Liu Y, Yin H, Li J, Li X, Zhao Y, Wang X, Ni F, Ma X, Li A, Xu SS, Bai G, Nevo E, Gao C, Ohm H, Kong L*, Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat. Science, 368, eaba5435 (2020).
35．Lin Q1, Zong Y1, Xue C1, Wang S, Jin S, Zhu Z, Wang Y, Anzalone AV, Raguram A, Doman JL, Liu DR, Gao C*, Prime genome editing in rice and wheat. Nature Biotechnology, 38, 582-585 (2020).
36．Zhang Y1, Ran Y1, Nagy I, Lenk I, Qiu JL, Asp T, Jensen CS, Gao C*, Targeted mutagenesis in ryegrass (Lolium spp.) using the CRISPR/Cas9 system. Plant Biotechnology Journal, 18, 1854-1856 (2020).
37．Li C1, Zhang R1, Meng X1, Chen S, Zong Y, Lu C, Qiu JL, Chen YH, Li J*, Gao C*, Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors. Nature Biotechnology, 38, 875-882 (2020).
38．Si X, Zhang H, Wang Y, Chen K, Gao C*, Manipulating gene translation in plants by CRISPR-Cas9-mediated genome editing of upstream open reading frames. Nature Protocols, 15, 338-363 (2020).
2019
39．Cao S1, Luo X1, Xie L1, Gao C, Wang D, Holt BF 3rd, Lin H, Chu C, Xia X*, The florigen interactor BdES43 represses flowering in the model temperate grass Brachypodium distachyon. Plant Journal, 102, 262-275 (2019).
40．Liu G1, Yin K1, Zhang Q, Gao C, Qiu JL*, Modulating chromatin accessibility by transactivation and targeting proximal dsgRNAs enhances Cas9 editing efficiency in vivo. Genome Biology, 20, 145 (2019).
41．He X, Wang Y, Yang F, Wang B, Xie H, Gu L, Zhao T, Liu X, Zhang D, Ren Q, Liu X, Liu Y, Gao C, Gu F*, Boosting activity of high-fidelity CRISPR/Cas9 variants using a tRNAGln-processing system in human cells. Journal of Biological Chemistry, 294, 9308-9315 (2019).
42．Zhang R1, Liu J1, Chai Z, Chen S, Bai Y, Zong Y, Chen K, Li J*, Jiang L*, Gao C*, Generation of herbicide tolerance traits and a new selectable marker in wheat using base editing. Nature Plants, 5, 480-485 (2019).
43．Cao X, Dong Z, Tian D, Dong L, Qian W, Liu J, Liu X, Qin H, Zhai W, Gao C, Zhang K*, Wang D*, Development and characterization of marker free and transgene insertion site defined transgenic wheat with improved grain storability and fatty acid content. Plant Biotechnology Journal, 18, 129-140 (2019).
44．Jin S1, Zong Y1, Gao Q1, Zhu Z, Wang Y, Qin P, Liang C, Wang D, Qiu J, Zhang F, Gao C*, Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice. Science, 364, 292-295 (2019).
45．Liu Q1, Wang C1, Jiao X, Zhang H, Song L, Li Y, Gao C, Wang K*, Hi-TOM: a platform for high-throughput tracking of mutations induced by CRISPR/Cas systems. Science China Life Sciences, 62, 1-7 (2019).
2018
46．Ji X1, Si X1, Zhang Y, Zhang H, Zhang F, Gao C*, Conferring DNA virus resistance with high specificity in plants using virus-inducible genome editing system. Genome Biology, 19, 197 (2018).
47．Li T1, Yang X1, Yu Y1, Si X, Zhai X, Zhang H, Dong W, Gao C*, Xu C*, Domestication of wild tomato is accelerated by genome editing. Nature Biotechnology, 36, 1160-1163 (2018).
48．Zong Y
1, Song Q
1, Li C, Jin S, Zhang D, Wang Y, Qiu JL,
Gao C*,
Efficient C-to-T base editing in plants using a fusion of nCas9 and human APOBEC3A.
Nature Biotechnology, 36, 950-953
(2018).
49．Xue C1, Zhang H1, Lin Q, Fan R, Gao C*, Manipulating mRNA splicing by base editing in plants. Science China Life Sciences, 61, 1293-1300 (2018).
50．Zhang H1, Si X1, Ji X1, Fan R, Liu J, Chen K, Wang D, Gao C*, Genome editing of upstream open reading frames (uORFs) enables translational control in plants. Nature Biotechnology, 36, 894-898 (2018).
51．Guo L1, Cao X1, Liu Y, Li J, Li Y, Li D, Zhang K, Gao C, Dong A, Liu X*, A chromatin loop represses WUSCHEL expression in Arabidopsis. Plant Journal, 94, 1083-1097 (2018).
52．Li C1, Zong Y1, Wang Y1, Jin S, Zhang D, Song Q, Zhang R, Gao C*, Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion. Genome Biology, 19, 59 (2018).
53．Liang Z, Chen K, Zhang Y, Yan Y, Gao C*, Genotyping genome-edited mutations in plants using CRISPR ribonucleoprotein complexes. Plant Biotechnology Journal, 16, 2053-2062 (2018).
54．Bhowmik P*, Ellison E, Polley B, Bollina V, Kulkarni M, Ghanbarnia K, Song H, Gao C, Voytas DF, Kagale S*, Targeted mutagenesis in wheat microspores using CRISPR/Cas9. Scientific Reports, 8, 6502 (2018).
55．Zhang Y1, Li D1, Zhang D, Zhao X, Cao X, Dong L, Liu J, Chen K, Zhang H, Gao C*, Wang D*, Analysis of the functions of TaGW2 homoeologs in wheat grain weight and protein content traits. Plant Journal, 94, 857-866 (2018).
56．Liang Z1, Chen K1, Zhang Y, Liu J, Yin K, Qiu JL, Gao C*, Genome editing of bread wheat using biolistic delivery of CRISPR/Cas9 in vitro transcripts or ribonucleoproteins. Nature Protocols, 13, 413-430 (2018).
57．Zhang D, Xu Z, Cao S, Chen K, Li S, Liu X, Gao C, Zhang B*, Zhou Y*, An uncanonical CCCH-tandem zinc finger protein represses secondary wall synthesis and controls mechanical strength in rice. Molecular Plant, 11, 163-174 (2018).
58．Meng X, Hu X, Liu Q, Song X, Gao C, Li J*, Wang K*, Robust genome editing of CRISPR-Cas9 at NAG PAMs in rice. Science China Life Sciences, 61, 122-125 (2018).
2017
59．Wang Y1, Yu H1, Tian C, Sajjad M, Gao C, Tong Y, Wang X*, Jiao Y*, Transcriptome association identifies regulators of wheat spike architecture. Plant Physiology, 175, 746-757 (2017).
60．Tu M, Lin L, Cheng Y, He X, Sun H, Xie H, Fu J, Liu C, Li J, Chen D, Xi H, Xue D, Liu Q, Zhao J, Gao C, Song Z, Qu J and Gu F*, A ’new lease of life’: FnCpf1 possesses DNA cleavage activity for genome editing in human cells. Nucleic Acids Research, 45, 11295-11304 (2017).
61．Zhang D1, Zhang H1, Li T, Chen K, Qiu JL, Gao C*, Perfectly matched 20-nucleotide guide RNA sequences enable robust genome editing using high-fidelity SpCas9 nucleases, Genome Biology, 18, 191 (2017).
62．Wang C1, Liu W1, Wang G1, Li J, Dong L, Han L, Wang Q, Tian J, Yu Y, Gao C and Kong Z*, KTN80 confers precision to microtubule severing by specific targeting of katanin complexes in plant cells. The EMBO Journal, 36, 3435-3447 (2017).
63．Meng X1, Yu H1, Zhang Y, Zhuang F, Song X, Gao S, Gao C*, Li J*, Construction of a genome-wide mutant library in rice using CRISPR/Cas9. Molecular Plant, 10, 1238-1241 (2017).
64．Zhang Y
1, Bai Y
1, Wu G, Zou S, Chen Y,
Gao C*, Tang D*,
Simultaneous modification of three homoeologs of
TaEDR1 by genome editing enhances powdery mildew resistance in wheat.
Plant Journal, 91, 714-724 (2017).
65．Li J1, Zhang H1, Si X, Tian Y, Chen K, Liu J, Chen H,Gao C*,Generation of thermosensitive male-sterile maize by targeted knockout of the
ZmTMS5 gene.
Journal of Genetics and Genomics, 44, 465-468 (2017).
66．Zong Y1, Wang Y1, Li C, Zhang R, Chen K, Ran Y, Qiu JL, Wang D, Gao C*, Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion. Nature Biotechnology, 35, 438-440 (2017).
67．Liang Z1, Chen K1, Li T, Zhang Y, Wang Y, Zhao Q, Liu J, Zhang H, Liu C, Ran Y, Gao C*, Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes. Nature Communications, 8, 14261 (2017).
68．Gil-Humanes J, Wang Y, Liang Z, Shan Q, Ozuna C, Sanchez-Leon S, Baltes N, Starker C, Francisco Barro F, Gao C, Voytas DF*, High-efficiency gene targeting in hexaploid wheat using DNA replicons and CRISPR/Cas9. Plant Journal, 89, 1251-1262 (2017).
2016
69．Li J1, Meng X1, Zong Y, Chen K, Zhang H, Liu J, Li J*, Gao C*, Gene replacements and insertions in rice by intron targeting using CRISPR/Cas9. Nature Plants, 2, 16139 (2016).
70．Zhang Y1, Liang Z1, Zong Y1, Wang Y, Liu J, Chen K, Qiu J, Gao C*, Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA. Nature Communications, 7, 12617 (2016).
71．Li X, Xia K, Liang Z, Chen K, Gao C, Zhang M*, MicroRNA393 is involved in nitrogen-promoted rice tillering through regulation of auxin signal transduction in axillary buds. Scientific Reports, 6, 32158 (2016).
2015
72．Ji X
1, Zhang H
1, Zhang Y, Wang Y,
Gao C*,
Establishing a CRISPR-Cas-like immune system conferring DNA virus resistance in plants.
Nature Plants, 1, 15144 (2015)
.
73．Wang S, Li S, Liu Q, Wu K, Zhang J, Wang S, Wang Y, Chen X, Zhang Y, Gao C, Wang F, Huang H, Fu X*, The OsSPL16-GW7 regulatory module determines grain shape and simultaneously improves rice yield and grain quality. Nature Genetics, 47, 949 (2015).
74．Shan Q, Zhang Y, Chen K, Zhang K, Gao C*, Creation of fragrant rice by targeted knockout of the OsBADH2 gene using TALEN technology. Plant Biotechnology Journal, 13, 791-800 (2015).
75．Zhang K, Liu J, Zhang Y, Yang Z, Gao C*, Biolistic genetic transformation of a wide range of Chinese elite wheat (Triticum aestivum L.) varieties. Journal of Genetics and Genomics, 42, 39-42 (2015).
2014
76．Shan Q, Wang Y, Li J, Gao C*, Genome editing in rice and wheat using the CRISPR/Cas system. Nature Protocols, 9, 2395-2410 (2014).
77．Wang Y1, Cheng X1, Shan Q, Zhang Y, Liu J, Gao C*, Qiu JL*, Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nature Biotechnology, 32, 947-951 (2014).
78．Xiao J, Xu S, Li C, Xu Y, Xing L, Niu Y, Huan Q, Tang Y, Zhao C, Wagner D, Gao C, Chong K*, O-GlcNAc-mediated interaction between VER2 and TaGRP2 elicits TaVRN1 mRNA accumulation during vernalization in winter wheat. Nature Communications, 5, 4572 (2014).
79．Liang Z, Zhang K, Chen K, Gao C*, Targeted mutagenesis in zea mays using TALENs and the CRISPR/Cas system. Journal of Genetics and Genomics, 41, 63-68 (2014).
80．Chen K, Shan Q, Gao C*, An efficient TALEN mutagenesis system in rice. Methods, 69, 2-8 (2014).
2013
81．Shan Q1, Wang Y1, Li J1, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Xi JJ, Qiu JL*, Gao C*, Targeted genome modification of crop plants using a CRISPR-Cas system. Nature Biotechnology, 31, 686-688 (2013).
82．Shan Q1, Wang Y1, Chen K1, Liang Z, Li J, Zhang Y, Zhang K, Liu J, Voytas D F, Zheng X, Zhang Y*, Gao C*, Rapid and efficient gene modification in rice and Brachypodium using TALENs. Molecular Plant, 6, 1365-1368 (2013).
Before 2011
83．Long D, Wu X, Yang Z, Lenk I, Nielsen KK, Gao C*, Comparison of three selectable marker genes for transformation of tall fescue (Festuca arundinacea Schreb.) plants by particle bombardment. In Vitro Cellular & Developmental Biology-Plant, 47, 658-666 (2011).
84．Gao C*, Liu J, Nielsen KK, Agrobacterium-mediated transformation of meadow fescue (Festuca pratensis Huds.). Plant Cell Reports, 28, 1431-1437 (2009).
85．Gao C*, Long D, Lenk I, Nielsen KK, Comparative analysis of transgenic tall fescue (Festuca arundinacea Schreb.) plants obtained by Agrobacterium-mediated transformation and particle bombardment. Plant Cell Reports, 27, 1601-1609 (2008).
86．Gao C*, Jiang L, Folling M, Han L, Nielsen KK, Generation of large numbers of transgenic Kentucky bluegrass (Poa pratensis L.) plants following biolistic gene transfer. Plant Cell Reports, 25, 19-25 (2006).
REVIEWS
1.Zhang XE*, Liu C*, Dai J*, Yuan Y*, Gao C*, Feng Y*, Wu B*, Wei P*, You C*, Wang X*, Si T*, Enabling technology and core theory of synthetic biology. SCIENCE CHINA Life Sciences, 66, 1742-1785 (2023).
2.
Gao C, Kikulwe E, Kuzma J, Lema M, Lidder P, Robinson J, Wessler J, and Zhao K, Gene editing and agrifood systems.
United Nations Food and Agriculture Organization (FAO),
https://doi.org/ 10.4060/cc3579en (2022).
3.Liu G
1, Lin Q
1, Jin S
1,
Gao C*, The CRISPR-Cas toolbox and gene editing technologies.
Molecular Cell, 82, 333-347 (2022).
4.Luo G
1, Najafi J
1, Correia P
1, Trinh M
1, Chapman E
1, Østerberg J, Thomsen H, Pedas P, Larson S,
Gao C, Poland J, Knudsen S, DeHaan, L, Palmgren M*, Accelerated Domestication of New Crops: Yield is Key.
Plant Cell Physiology, 63, 1624-1640 (2022).
5.Gao C*, Genome engineering for crop improvement and future agriculture. Cell, 184, 1621-1635 (2021).
6.Zhu H1, Li C1, Gao C*, Applications of CRISPR-Cas in agriculture and plant biotechnology. Nature Reviews Molecular Cell Biology, 21, 661-677 (2020).
7.Chen K, Gao C*, Genome-edited crops: how to move them from laboratory to market. Frontiers of Agricultural Science and Engineering, 7, 181-187 (2020).
8.DeHaan L, Larson S, López-Marqués RL, Wenkel S, Gao C, Palmgren M, Roadmap for accelerated domestication of an emerging perennial grain crop. Trends in Plant Science, 25, 525-537 (2020).
9.López-Marqués RL*, Nørrevang AF, Ache P, Moog M, Visintainer D, Wendt T, Østerberg JT, Dockter C, Jørgensen ME, Salvador AT, Hedrich R, Gao C, Jacobsen SE, Shabala S, Palmgren M*, Prospects for the accelerated improvement of the resilient crop quinoa. Journal of Experimental Botany, 71, 5333-5347 (2020).
10.Zhang Y, Pribil M, Palmgren, M*, Gao C*, A CRISPR way for accelerating improvement of food crops. Nature Food, 1, 200-205 (2020).
11.Hickey LT*, N Hafeez A, Robinson H, Jackson SA, Leal-Bertioli SCM, Tester M, Gao C, Godwin ID, Hayes BJ, Wulff BBH*, Breeding crops to feed 10 billion. Nature Biotechnology, 37, 744-754 (2019).
12.Chen K1, Wang Y1, Zhang R, Zhang H, Gao C*, CRISPR/Cas Genome editing and precision plant breeding in agriculture. Annual Review of Plant Biology, 70, 667-697 (2019).
13.Ji X, Wang D, Gao C*, CRISPR editing-mediated antiviral immunity: a versatile source of resistance to combat plant virus infections. Science China Life Sciences, 62, 1246-1249 (2019).
14.Wang M1, Wang S1, Liang Z, Shi W, Gao C*, Xia G*, From genetic stock to genome editing: gene exploitation in wheat. Trends in Biotechnology, 36, 160-172 (2018).
15.Zhang Y, Massel K, Godwin I, Gao C*, Applications and potential of genome editing in crop improvement. Genome Biology, 19, 210 (2018).
16.Zhang Y, Gao C*, Recent advances in DNA-free editing and precise base editing in plants. Emerging Topics in Life Sciences, 1, 161-168 (2017).
17.Yin K,
Gao C*, Qiu JL*,
Progress and prospects in plant genome editing.
Nature Plants, 3, 17107 (2017).
18.Ran Y*, Liang Z,
Gao C*,
Current and future editing reagent delivery systems for plant genome editing.
Science China Life Science, 60, 490-505 (2017).
19.Gao C*, Genome editing in crops: from bench to field. National Science Review, 2, 13-15 (2015).
20.Chen K, Gao C*, Targeted genome modification technologies and their applications in crop improvements. Plant Cell Reports, 33, 575-583 (2014).
21.Voytas D F*, Gao, C*, Precision genome engineering and agriculture: opportunities and regulatory challenges. PLoS Biology, 12, e1001877 (2014).
22.Chen K, Gao C*, TALENs: Customizable Molecular DNA Scissors for Genome Engineering of Plants. Journal of Genetics and Genomics, 40, 271-279 (2013).
23.Brkljacic J, Grotewold E, Scholl R, Mockler T, Garvin DF, Vain P, Brutnell T, Sibout R, Bevan M, Budak H, Caicedo AL, Gao C, Gu Y, Hazen SP, Holt BF 3rd, Hong SY, Jordan M, Manzaneda AJ, Mitchell-Olds T, Mochida K, Mur LA, Park CM, Sedbrook J, Watt M, Zheng SJ, Vogel JP*, Brachypodium as a model for the grasses: today and the future. Plant Physiology, 157, 3-13 (2011).
COMMENTARY
1.Liang R, Gao C*, Creating one-line hybrid crops by synthetic apomixes. Molecular Plant, 17, 1–3 (2024).
2.Zou J, Huang Y, Gao C*, Wang K*, Unlocking crop diversity: enhancing variations through genome editing. Science Bulletin, 15, 281-284 (2023).
3.Xue C, Gao C, Engineered upstream open reading frames predictably downregulate mRNA translation in plants. Nature Biotechnology, 41, 1694-1695 (2023).
4.Hu J, Gao C*, CRISPR-edited plants by grafting. Nature Biotechnology, 41, 909-910 (2023).
5.Wei W*, Gao C*, Gene editing: from technologies to applications in research and beyond. Science China Life Sciences, 65, 657-659 (2022).
6.Gao C, Chen J, CRISPR Adventures in China. The CRISPR Journal, 4, 304-306 (2021).
7.Gao C*, Precision plant breeding using genome editing technologies. Transgenic Research, 28, 53-55 (2019).
8.Li J*, Gao C*, Preface to the special topic on genome editing research in China. National Science Review, 6, 389-390 (2019).
9.Gao C*, The future of CRISPR technologies in agriculture. Nature Reviews Molecular Cell Biology, 19, 275-276 (2018).
10.Wang H, Li J, Li W, Gao C, Wei W*, CRISPR twins: a condemnation from Chinese academic societies. Nature, 564, 345 (2018). (SCI Citations: 4)
11.Jiao R*, Gao C*, Anything impossible with CRISPR/Cas9?. Science China Life Sciences, 60, 445-446 (2017).
12.Jiao R*, Gao C*, The CRISPR/Cas9 genome editing revolution. Journal of Genetics and Genomics, 43, 227-228 (2016).
BOOK CHAPTERS
1.Luo G, Li B, Gao C, Protoplast Isolation and Transfection in Wheat. Methods in Molecular Biology, 2464, 131-141 (2022).
2.Li J, Meng X, Li J, Gao C*, Gene Replacement by Intron Targeting with CRISPR-Cas9. In: Qi Y. (eds) Plant Genome Editing with CRISPR Systems. Methods in Molecular Biology, 1917, 285-296 (2019).
3.Liang Z, Chen K, Gao C*, Biolistic Delivery of CRISPR/Cas9 with Ribonucleoprotein Complex in Wheat. In: Qi Y. (eds) Plant Genome Editing with CRISPR Systems. Methods in Molecular Biology, 1917, 311-326 (2019).
4.Wang Y, Zong Y, Gao C*, Targeted Mutagenesis in Hexaploid Bread Wheat Using the TALEN and CRISPR/Cas Systems. In: Bhalla P., Singh M. (eds) Wheat Biotechnology. Methods in Molecular Biology, 1679, 169-185 (2017).
5.Liang Z, Zong Y,
Gao C*,
An Efficient Targeted Mutagenesis System Using CRISPR/Cas in Monocotyledons.
Current Protocols in Plant Biology 1, 329-344 (2016).
6.Zhang Y, Li J, Gao C*, Generation of Stable Transgenic Rice (Oryza sativa L.) by Agrobacterium-Mediated Transformation. Current Protocols in Plant Biology, 1, 235-246 (2016).
7.Chen K, Gao C*, Developing CRISPR technology in major crop plants. F. Zhang et al. (eds.), Advances in New Technology for Targeted Modification of Planty Genomes. p145-161 (2015).
8.Chen K, Gao C*, Targeted gene mutation in plants. X.-Q. Li et al. (eds.), Somatic Genome Manipulation. p253-272 (2015).
9.Gao C*, Nielsen KK, Comparison Between Agrobacterium-Mediated and Direct Gene Transfer Using the Gene Gun. Methods in Molecular Biology, 940, 3-16 (2013).
