--中国科学院遗传与发育生物学研究所

姓　　名：	宋庆鑫
职　　称：	研究员
职　　务：
电话/传真：
电子邮件：	qxsong@genetics.ac.cn
实验室主页：
研究方向：	大豆进化与遗传改良

简历介绍：

宋庆鑫，研究员，博士生导师，课题组长

国家自然科学基金青年科学基金项目（A类）获得者。长期从事大豆进化与遗传改良研究，在Nature Genetics、Plant Cell、Molecular Plant等期刊发表论文50余篇；主持国家重点研发计划青年科学家项目、国家自然科学基金面上项目等科研项目；获农业农村部“神农青年英才”、中国农学会青年科技奖、卫志明青年创新奖等奖项；担任Genome Biology、JIPB、Crop Journal、Plant Innovation等杂志编委；兼任中国植物学会植物生理及分子生物学专业委员会委员、中国植物生理与植物分子生物学学会遗传与分子生物学专业委员会委员等。

教育经历

2002 - 2006，沈阳农业大学，学士

2006 - 2013，中国科学院遗传与发育生物学研究所，博士

工作经历

2013 - 2018，美国The University of Texas at Austin，博士后

2018 - 2026，南京农业大学，教授

2026 - 至今，中国科学院遗传与发育生物学研究所，研究员

研究领域：

聚焦大豆进化机制解析与高油高产遗传改良，探索大豆远缘杂交育种新途径。

1 大豆进化与驯化的遗传和表观遗传调控：基于基因组、表观组、代谢组等多组学大数据，揭示大豆进化与驯化的遗传和表观遗传调控规律，解析古多倍化对基因组与性状演化的塑造作用，探索人工多倍化育种新途径，为优异种质创制提供基因资源与理论支撑。

2 大豆高油高产性状耦合机制解析与精准设计：整合群体遗传学、基因编辑与人工智能等多学科手段，系统解析高油与高产性状耦合的遗传基础与调控网络，构建大豆表型智能预测模型，实现高油高产基因型的精准设计与重构，定向创制高油高产协同突破的大豆新种质。

3 高产耐逆远缘杂交大豆种质创制与创新应用：解析多年生野生大豆的遗传进化规律，精准挖掘高产、耐逆等优异性状关键调控基因，破解其与栽培大豆远缘杂交的生殖隔离壁垒，开发高效杂交与染色体工程等关键技术，创制高产耐逆远缘杂交大豆新种质，并推动其规模化创新应用。

社会任职：

获奖及荣誉：

承担科研项目情况：

代表论著：

1. Jiang X, Zhang M, Yuan X, Wang L, Jiao W, Mao J, Ye W, Yu D, Tian Z, Song Q*. (2026) Population epigenomics reveals epigenetic drivers of replicated evolution and missing heritability in soybean. Molecular Plant. 19:1100-1116

2. Wang L, Jiang X, Jiao W, Mao J, Ye W, Cao Y, Chen Q and Song Q*. (2025) Pangenome analysis provides insights into legume evolution and breeding. Nature Genetics. 57:2052-2061

3. Wang X^#, Jiang X^#, Yuan X, Zhou Z, Zhao Z, Wang L, Jiao W, Ye W and Song Q*. (2025) Transcriptome-Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean. Advanced Science. 11:e16794

4. Jiao W^#, Wang M^#, Guan Y^#, Guo W^#, Zhang C, Wei Y, Zhao Z, Ma H, Wang L, Jiang X, Ye W, Cao D* and Song Q*. (2024) Transcriptional regulatory network reveals key transcription factors for regulating agronomic traits in soybean. Genome Biology, 25:313

5. Yuan X^#, Jiang X^#, Zhang M^#, Wang L, Jiao W, Chen H, Mao J, Ye W and Song Q*. (2024) Integrative omics analysis elucidates the genetic basis underlying seed weight and oil content in soybean. Plant Cell, 36: 2160–2175

6. Feng S, Jiang X, Huang Z, Li F, Wang R, Yuan X, Sun Z, Tan H, Zhong L, Li S, Cheng Y, Bao M, Qiao H, Song Q*, Wang J* and Zhang F*. (2024) DNA methylation remodeled amino acids biosynthesis regulates flower senescence in carnation (Dianthus caryophyllus). New Phytologist, 241:1605-1620

7. Wang L, Zhang M, Li M, Jiang X, Jiao W and Song Q*. (2023) A telomere-to-telomere gap-free assembly of soybean genome. Molecular Plant, 16:1711-1714

8. Cao S, Chen K, Lu K, Chen S, Zhang X, Shen C, Zhu S, Niu Y, Fan L, Chen ZJ*, Xu J* and Song Q*. (2023) Asymmetric variation in DNA methylation during domestication and de-domestication of rice. Plant Cell. 35:3429-3443

9. Zhang M^#, Zhang X^#, Jiang X^#, Qiu L^#, Jia G, Wang L, Ye W and Song Q*. (2022) iSoybean: a database for the mutational fingerprints of soybean. Plant Biotechnology Journal, 20:1435-1437

10. Cao S, Wang L, Han T, Ye W, Liu Y, Sun Y, Moose SP, Song Q* and Chen ZJ*. (2022) Small RNAs mediate transgenerational inheritance of genome-wide trans-acting epialleles in maize. Genome Biology, 23:53

11. Yuan J, Sun H, Wang Y, Li L, Chen S, Jiao W, Jia G, Wang L, Mao J, Ni Z, Wang X and Song Q*. (2022) Open chromatin interaction maps reveal functional regulatory elements and chromatin architecture variations during wheat evolution. Genome Biology. 23:34

12. Wang L, Jia G, Jiang X, Cao S, Chen ZJ and Song Q*. (2021) Altered chromatin architecture and gene expression during polyploidization and domestication of soybean. Plant Cell. 33: 1430-1446

13. Yuan J, Jiao W, Liu Y, Ye W, Wang X, Liu B, Song Q* and Chen ZJ*. (2020) Dynamic and reversible DNA methylation changes induced by genome separation and merger of polyploid wheat. BMC Biology. 18:171

14. Liu Y^#, Yuan J^#*, Jia G, Ye W, Chen ZJ* and Song Q*. (2020) Histone H3K27 dimethylation landscapes contribute to genome stability and genetic recombination during wheat polyploidization. Plant Journal. 105:678-690

15. Chen ZJ^#*, Sreedasyam A^#, Ando A^#, Song Q^#, De Santiago LM^#, ..., Grimwood J* and Schmutz J. (2020) Genomic diversifications of five Gossypium allopolyploid species and their impact on cotton improvement. Nature Genetics. 52:525-533

16. Song Q^#, Ando A^#, Jiang N, Ikeda Y and Chen ZJ*. (2020) Single-cell RNA-seq analysis reveals ploidy-dependent and cell-specific transcriptome changes in Arabidopsis female gametophytes. Genome Biology. 21:178

17. Yin D^#*, Ji C^#, Song Q^#, Zhang W^#, Zhang X, Zhao K, Chen CY, Wang C, He G, Liang Z, Ma X, Li Z, Tang Y, Wang Y, Li K, Ning L, Zhang H, Zhao K, Li X, Yu H, Lei Y, Wang M, Ma L, Zheng H, Zhang Y, Zhang J*, Hu W* and Chen ZJ*. (2020) Comparison of Arachis monticola with Diploid and Cultivated Tetraploid Genomes Reveals Asymmetric Subgenome Evolution and Improvement of Peanut. Advanced Science. 7:1901672

18. Song Q^#, Huang TY^#, Yu HH, Ando A, Mas P, Ha M and Chen ZJ*. (2019) Diurnal regulation of SDG2 and JMJ14 by circadian clock oscillators orchestrates histone modification rhythms in Arabidopsis. Genome Biology. 20:170

19. Song Q, Ando A, Xu D, Fang L, Zhang T, Huq E, Qiao H, Deng XW* and Chen ZJ*. (2018) Diurnal down-regulation of ethylene biosynthesis mediates biomass heterosis. PNAS. 115: 5606-5611.

20. Song Q, Zhang T, Stelly D and Chen ZJ*. (2017) Epigenomic and functional analyses revealed roles of epialleles in the loss of photoperiod sensitivity during domestication of allotetraploid cottons. Genome Biology. 18:99.

21. Song Q, Guan X and Chen ZJ*. (2015) Dynamic Roles for Small RNAs and DNA Methylation during Ovule and Fiber Development in Allotetraploid Cotton. PLoS Genetics 11:e1005724.

22. Miller M^#, Song Q^#, Shi X, Juenger TE and Chen ZJ*. (2015) Natural variation in timing of stress-responsive gene expression predicts heterosis in intraspecific hybrids of Arabidopsis. Nature Communications 6:7453.

23. Song Q and Chen ZJ*. (2015) Epigenetic and developmental regulation in plant polyploids. Current Opinion in Plant Biology 24:101-109.

24. Song QX^#, Li QT^#, Liu YF, Zhang FX, Ma B, Zhang WK, Man WQ, Du WG, Wang GD, Chen SY* and Zhang JS*. (2013) Soybean GmbZIP123 gene enhances lipid content in the seeds of transgenic Arabidopsis plants. Journal of Experimental Botany 64:4329-4341.

25. Song QX, Lu X, Li QT, Chen H, Hu XY, Ma B, Zhang WK, Chen SY* and Zhang JS*. (2013) Genome-wide analysis of DNA methylation in soybean. Molecular Plant 6:1961-1974.

26. Song QX, Liu YF, Hu XY, Zhang WK, Ma B, Chen SY* and Zhang JS*. (2011) Identification of miRNAs and their target genes in developing soybean seeds by deep sequencing. BMC Plant Biology 11:5.